Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1911364 | 0.89 | REN (0.56) | RENCDK9 | |
| SCHEMBL10283299 | 0.89 | REN (0.57) | RENCDK9 | |
| SCHEMBL1911386 | 0.88 | REN (0.56) | RENCDK9 | |
| SCHEMBL1911408 | 0.83 | REN (0.55) | REN | |
| SCHEMBL90523 | 0.79 | REN (0.61) | REN | |
| SCHEMBL90042 | 0.78 | REN (0.63) | REN | |
| SCHEMBL8237597 | 0.78 | REN (0.57) | REN | |
| SCHEMBL89684 | 0.77 | REN (0.59) | REN | |
| SCHEMBL90027 | 0.77 | REN (0.43) | REN | |
| SCHEMBL1911411 | 0.77 | REN (0.54) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2420491-A1 | 3 , 5-substitued piperidine compounds as renin inhibitors | Novartis AG (CH) | 2012-02-22 | — | — | EP | disclosed |