Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10282959 | 0.89 | REN (0.59) | RENCDK9 | |
| SCHEMBL1911386 | 0.86 | REN (0.56) | RENCDK9 | |
| SCHEMBL1911364 | 0.85 | REN (0.56) | RENCDK9 | |
| SCHEMBL89706 | 0.78 | REN (0.57) | REN | |
| SCHEMBL10282964 | 0.78 | USP30 (0.39) | REN | |
| SCHEMBL90559 | 0.78 | REN (0.54) | REN | |
| SCHEMBL89618 | 0.77 | REN (0.42) | REN | |
| SCHEMBL1911408 | 0.76 | REN (0.55) | REN | |
| SCHEMBL1911417 | 0.75 | HPGD (0.46) | REN | |
| SCHEMBL1911411 | 0.75 | REN (0.54) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2420491-A1 | 3 , 5-substitued piperidine compounds as renin inhibitors | Novartis AG (CH) | 2012-02-22 | — | — | EP | disclosed |