SCHEMBL1028307

SCHEMBL1028307

COC(=O)c1cc(N)cc(O)c1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 5/20 0.73
CA1 P00915 5/20 0.73
CA2 P00918 5/20 0.73
CA7 P43166 5/20 0.73
CA9 Q16790 5/20 0.73
CA14 Q9ULX7 5/20 0.73
GAA P10253 4/20 0.53
KDM4E B2RXH2 4/20 0.53
XDH P47989 2/20 0.53
LMNA P02545 2/20 0.53
POLB P06746 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
NFKB1 P19838 1/20 0.53
GFER P55789 1/20 0.53
NFKB2 Q00653 1/20 0.53
RELA Q04206 1/20 0.53
FUT7 Q11130 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
ATAD2 Q6PL18 1/20 0.48
CNR2 P34972 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30554557 1.00 CA12 (0.73) CA12CA1CA2CA7CA9
SCHEMBL30554535 1.00 CA12 (0.73) CA12CA1CA2CA7CA9
SCHEMBL111187 0.87 CA12 (0.58) CA12CA1CA2CA7CA9
SCHEMBL654773 0.87 CA1 (0.58) CA12CA1CA2CA7CA9
Hydrochloric Acid SCHEMBL111186 0.85 CA12 (0.56) CA12CA1CA2CA7CA9
Hydrochloric Acid SCHEMBL9494959 0.85 CA1 (0.56) CA12CA1CA2CA7CA9
SCHEMBL46504 0.85 CA12 (0.91) CA12CA1CA2CA7CA9
Methyl 3,5-Dihydroxybenzoate SCHEMBL38869 0.85 CA1 (1.00) CA12CA1CA2CA7CA9
SCHEMBL8410461 0.82 ATAD2 (0.60) CA12CA1CA2CA7CA9
SCHEMBL10600019 0.80 CA12 (0.50) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118879153-A Preparation process of wear-resistant epoxy resin for floor paint 广东绿树环保涂料科技有限公司 2024-11-01 CN claimed
CN-116730657-B Cold patch asphalt mixture and preparation method thereof 芜湖城瑞路桥建设有限公司 2024-07-12 CN claimed
CN-116730657-A Cold patch asphalt mixture and preparation method thereof 芜湖城瑞路桥建设有限公司 2023-09-12 CN claimed
US-20260022099-A1 ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF NEXYS THERAPEUTICS, INC. (US) 2026-01-22 US disclosed
WO-2025242903-A1 COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF PROLIFERATIVE DISEASES ONCO3R THERAPEUTICS BV (BE) 2025-11-27 WO disclosed
US-12371408-B2 Aryl hydrocarbon receptor agonists and uses thereof NEXYS THERAPEUTICS, INC. (US) 2025-07-29 US disclosed
CN-120202243-A Thermosetting resin composition, cured film, substrate, and electronic component 捷恩智株式会社 2025-06-24 CN disclosed
US-12168646-B2 Aryl hydrocarbon receptor agonists and uses thereof NEXYS THERAPEUTICS, INC. (US) 2024-12-17 US disclosed
CN-118891251-A Aryl hydrocarbon receptor agonists and uses thereof 奈可萨斯医药有限公司 2024-11-01 CN disclosed
CN-118879153-A Preparation process of wear-resistant epoxy resin for floor paint 广东绿树环保涂料科技有限公司 2024-11-01 CN disclosed
US-20240279185-A1 ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF NEXYS THERAPEUTICS, INC. (US) 2024-08-22 US disclosed
WO-2004060376-A1 THE R-ISOMER OF BETA AMINO ACID COMPOUNDS AS INTEGRIN RECEPTOR ANTAGONISTS DERIVATIVES PHARMACIA CORPRATION (US) 2004-07-22 WO disclosed
WO-2003101959-A1 PYRROLE COMPOUNDS FOR THE TREATMENT OF PROSTAGLANDIN MEDIATED DISEASES GLAXO GROUP LIMITED (GB) 2003-12-11 WO disclosed
EP-1021411-B1 BENZAMIDE DERIVATIVES AS THROMBIN INHIBITORS GLAXO GROUP LTD (GB) 2003-03-05 EP disclosed
US-6326386-B1 ANTICOAGULANT GLAXO GROUP LIMITED (GB) 2001-12-04 US disclosed
EP-1021411-A1 BENZAMIDE DERIVATIVES AS THROMBIN INHIBITORS GLAXO GROUP LIMITED (GB) 2000-07-26 EP disclosed
WO-1997022589-A1 BENZAMIDE DERIVATIVES AS THROMBIN INHIBITORS GLAXO GROUP LIMITED (GB) 1997-06-26 WO disclosed
EP-0134782-A1 PROCESS FOR THE PREPARATION OF 3-AMINO-5-HYDROXYBENZOIC ACIDS AND DERIVATIVES AND ANALOGUES THEREOF THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 1985-03-27 EP disclosed
EP-0134782-A4 PROCESS FOR THE PREPARATION OF 3-AMINO-5-HYDROXYBENZOIC ACIDS AND DERIVATIVES AND ANALOGUES THEREOF. UNIV AUSTRALIAN (AU) 1985-02-18 EP disclosed
WO-1984000750-A1 PROCESS FOR THE PREPARATION OF 3-AMINO-5-HYDROXYBENZOIC ACIDS AND DERIVATIVES AND ANALOGUES THEREOF UNIV AUSTRALIAN (AU) 1984-03-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12371408-B2 Aryl hydrocarbon receptor agonists and uses thereof AHR, ARNT, NR1H2 CA12 4778/4885CA1 4417/4885CA2 4744/4885
US-20260022099-A1 ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF AHR, NR1H4, CNR1 CA12 4257/4885CA1 2945/4885CA2 3205/4885
US-20240279185-A1 ARYL HYDROCARBON RECEPTOR AGONISTS AND USES THEREOF AHR, ARNT, NR1H2 CA12 4778/4885CA1 4417/4885CA2 4744/4885
US-12168646-B2 Aryl hydrocarbon receptor agonists and uses thereof AHR, ARNT, NR1H2 CA12 4778/4885CA1 4417/4885CA2 4744/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.