Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10246340 | 1.00 | ALDH1A1 (0.49) | ALDH1A1LMNACHRM2OPRL1POLB | |
| SCHEMBL698466 | 0.82 | ALDH1A1 (0.54) | ALDH1A1LMNACHRM2OPRL1POLB | |
| SCHEMBL3408748 | 0.76 | OPRM1 (0.57) | ALDH1A1LMNACHRM2OPRL1POLB | |
| SCHEMBL639574 | 0.75 | OPRL1 (0.73) | ALDH1A1LMNACHRM2OPRL1POLB | |
| SCHEMBL3409814 | 0.75 | ALDH1A1 (0.51) | ALDH1A1LMNACHRM2OPRL1POLB | |
| SCHEMBL702465 | 0.73 | ALDH1A1 (0.57) | ALDH1A1LMNACHRM2OPRL1POLB | |
| SCHEMBL3406351 | 0.73 | POLB (0.62) | ALDH1A1LMNACHRM2OPRL1POLB | |
| SCHEMBL701023 | 0.73 | OPRM1 (0.63) | OPRM1OPRD1OPRK1 | |
| SCHEMBL20493531 | 0.73 | ALDH1A1 (0.48) | ALDH1A1LMNACHRM2POLBMEN1 | |
| SCHEMBL20493533 | 0.73 | ALDH1A1 (0.48) | ALDH1A1LMNACHRM2POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124624-B2 | Substituted sulfonamide compounds | GRUENENTHAL GMBH (DE) | 2012-02-28 | — | — | US | disclosed |
| US-20090264407-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264407-A1 | Substituted Sulfonamide Compounds | CNR1, SUCNR1, OPRL1 | ALDH1A1 958/4885LMNA 2119/4885CHRM2 687/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.