Ethylene

Ethylene

SCHEMBL1028334

C=C.C=CCC(=O)OCC(C)OC(=O)CC=C

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
TDP1 Q9NUW8 1/20 0.33
HTT P42858 1/20 0.33
PRKCA P17252 1/20 0.31
ALDH1A1 P00352 1/20 0.30
GAA P10253 1/20 0.30
FAAH O00519 1/20 0.30
MGLL Q99685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10051592 0.98 TSHR (0.42) TSHRTDP1HTTPRKCAALDH1A1
Ethylene Glycol SCHEMBL1834312 0.93 TSHR (0.39) TSHRTDP1HTTPRKCA
SCHEMBL1510285 0.84 TSHR (0.57) TSHRTDP1HTTPRKCAALDH1A1
SCHEMBL8655058 0.79 MAPT (0.47) TSHRTDP1HTTALDH1A1GAA
SCHEMBL10295951 0.79 ALDH1A1 (0.42) HTTPRKCAALDH1A1
SCHEMBL2986931 0.79 LMNA (0.33) TSHRTDP1ALDH1A1GAAFAAH
SCHEMBL1028335 0.77 HTT (0.42) TSHRTDP1HTTALDH1A1FAAH
SCHEMBL6744553 0.77 HTT (0.34) TSHRHTTALDH1A1GAA
SCHEMBL207281 0.76
SCHEMBL14088758 0.76 MMP1 (0.32) TSHRTDP1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130289605-A1 Atraumatic Occlusion Balloons and Skirts, and Methods of Use Thereof GENZYME CORPORATION 2013-10-31 US claimed
US-8491623-B2 Atraumatic occlusion balloons and skirts, and methods of use thereof PLUROMED, INC. (US) 2013-07-23 US claimed
JP-4815347-B2 2011-11-16 JP claimed
EP-2061547-A2 ATRAUMATIC OCCLUSION BALLOONS AND SKIRTS, AND METHODS OF USE THEREOF Pluromed, Inc. (US) 2009-05-27 EP claimed
US-20080215036-A1 Atraumatic Occlusion Balloons and Skirts, and Methods of Use Thereof PLUROMED, INC. (US) 2008-09-04 US claimed
WO-2008033728-A2 ATRAUMATIC OCCLUSION BALLOONS AND SKIRTS, AND METHODS OF USE THEREOF PLUROMED, INC. (US) 2008-03-20 WO claimed
JP-2007502660-A 2007-02-15 JP claimed
EP-1656177-A1 MEDICAL BALLOONS Boston Scientific Limited (BB) 2006-05-17 EP claimed
WO-2005021083-A1 MEDICAL BALLOONS BOSTON SCIENTIFIC LIMITED (BB) 2005-03-10 WO claimed
US-20160338707-A1 Atraumatic Occlusion Balloons and Skirts, and Methods of Use Thereof GENZYME CORP (US) 2016-11-24 US disclosed
EP-2274044-B1 FLUID TRANSFER ASSEMBLIES AND RELATED METHODS SAINT GOBAIN PERFORMANCE PLAST (US) 2016-11-16 EP disclosed
EP-1545394-B1 MEDICAL DEVICES BOSTON SCIENT LTD (BM) 2016-05-11 EP disclosed
US-9259563-B2 Fluid transfer assemblies and related methods SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION (US) 2016-02-16 US disclosed
US-9180620-B2 Medical balloons BOSTON SCIENTIFIC SCIMED, INC. (US) 2015-11-10 US disclosed
WO-2004019821-A1 MEDICAL DEVICES AND METHODS OF MAKING THE SAME BOSTON SCIENTIFIC LIMITED (BB) 2004-03-11 WO disclosed
US-20040044397-A1 Medical devices and methods of making the same BOSTON SCIENTIFIC SCIMED, INC. 2004-03-04 US disclosed
WO-2002056930-A9 MULTILAYER MEDICAL DEVICE SCIMED LIFE SYSTEMS INC (US) 2003-11-20 WO disclosed
EP-1337396-A2 MULTILAYER MEDICAL DEVICE Scimed Life Systems, Inc. (US) 2003-08-27 EP disclosed
US-20020165523-A1 Multilayer medical device BOSTON SCIENTIFIC SCIMED, INC. 2002-11-07 US disclosed
WO-2002056930-A2 MULTILAYER MEDICAL DEVICE SCIMED LIFE SYSTEMS, INC. (US) 2002-07-25 WO disclosed