Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | UBE2M | P61081 | 3/20 | 0.33 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10285566 | 0.93 | UBE2M (0.36) | HSD11B1CCR5HTR2AUBE2MDCUN1D1 | |
| SCHEMBL10285204 | 0.91 | KCNH2 (0.42) | HTR2AKCNH2OPRM1 | |
| SCHEMBL14279739 | 0.83 | NR1H4 (0.40) | HSD11B1CCR5HTR2AUBE2MDCUN1D1 | |
| SCHEMBL10285880 | 0.82 | UBE2M (0.35) | HSD11B1CCR5HTR2AUBE2MDCUN1D1 | |
| SCHEMBL2796897 | 0.80 | KCNH2 (0.41) | UBE2MDCUN1D1KCNH2 | |
| SCHEMBL10285621 | 0.80 | OPRM1 (0.39) | CCR5HTR2ANR1H4KCNH2OPRM1 | |
| SCHEMBL2800308 | 0.79 | UBE2M (0.42) | CCR5UBE2MDCUN1D1NR1H4KCNH2 | |
| SCHEMBL2800489 | 0.79 | KCNH2 (0.52) | UBE2MDCUN1D1KCNH2OPRM1 | |
| SCHEMBL10285355 | 0.79 | DCUN1D1 (0.37) | HSD11B1CCR5UBE2MDCUN1D1 | |
| SCHEMBL14279427 | 0.79 | KCNH2 (0.37) | KCNH2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2468743-A1 | Nitrogen-containing bicyclic compounds useful as antibacterial agents | Toyama Chemical Co., Ltd. (JP) | 2012-06-27 | — | — | EP | disclosed |