Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCUN1D1 | Q96GG9 | 12/20 | 0.37 |
| ▸ | UBE2M | P61081 | 11/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 2/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12000102 | 0.89 | LMNA (0.42) | DCUN1D1UBE2MLMNA | |
| SCHEMBL10285880 | 0.83 | UBE2M (0.35) | DCUN1D1UBE2MHSD11B1CCR5LMNA | |
| SCHEMBL14279739 | 0.82 | NR1H4 (0.40) | DCUN1D1UBE2MHSD11B1CCR5PLA2G7 | |
| SCHEMBL2795740 | 0.81 | UBE2M (0.41) | DCUN1D1UBE2MCCR5LMNA | |
| SCHEMBL10285566 | 0.80 | UBE2M (0.36) | DCUN1D1UBE2MHSD11B1CCR5 | |
| SCHEMBL10285200 | 0.79 | HSD11B1 (0.35) | DCUN1D1UBE2MHSD11B1CCR5 | |
| SCHEMBL10285574 | 0.79 | KCNH2 (0.37) | HSD11B1CCR5 | |
| SCHEMBL12000155 | 0.79 | LMNA (0.42) | DCUN1D1UBE2MCCR5LMNA | |
| SCHEMBL10285621 | 0.79 | OPRM1 (0.39) | CCR5 | |
| SCHEMBL10285209 | 0.78 | KCNH2 (0.37) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2468743-A1 | Nitrogen-containing bicyclic compounds useful as antibacterial agents | Toyama Chemical Co., Ltd. (JP) | 2012-06-27 | — | — | EP | disclosed |