Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 16/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10285574 | 0.91 | KCNH2 (0.37) | KCNH2HTR2ACCR5NR1H4 | |
| SCHEMBL10285880 | 0.90 | UBE2M (0.35) | KCNH2HTR2ACCR5NR1H4 | |
| SCHEMBL12000122 | 0.89 | KCNH2 (0.45) | KCNH2NR1H4 | |
| SCHEMBL10285211 | 0.86 | STAT3 (0.34) | KCNH2CCR5NR1H4 | |
| SCHEMBL10285621 | 0.85 | OPRM1 (0.39) | KCNH2HTR2ACCR5CNR2NR1H4 | |
| SCHEMBL10285573 | 0.83 | GPR119 (0.38) | KCNH2CCR5NR1H4 | |
| SCHEMBL12000105 | 0.82 | KCNH2 (0.46) | KCNH2HTR2A | |
| SCHEMBL2796266 | 0.81 | KCNH2 (0.53) | KCNH2CNR2 | |
| SCHEMBL10285204 | 0.81 | KCNH2 (0.42) | KCNH2HTR2A | |
| SCHEMBL10285571 | 0.81 | CNR2 (0.41) | KCNH2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2468743-A1 | Nitrogen-containing bicyclic compounds useful as antibacterial agents | Toyama Chemical Co., Ltd. (JP) | 2012-06-27 | — | — | EP | disclosed |
| EP-1900732-A1 | NOVEL NITROGENATED HETEROCYCLIC COMPOUND AND SALT THEREOF | TOYAMA CHEMICAL CO., LTD. (JP) | 2008-03-19 | — | — | EP | disclosed |