Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.42 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19874109 | 0.85 | DRD2 (0.40) | HTR2ADRD2DRD3SIGMAR1ALDH1A1 | |
| SCHEMBL19874111 | 0.85 | DRD2 (0.40) | HTR2ADRD2DRD3SIGMAR1ALDH1A1 | |
| SCHEMBL19886482 | 0.84 | DRD2 (0.39) | ACHEDRD2DRD3ALDH1A1 | |
| SCHEMBL19874416 | 0.82 | DRD2 (0.40) | ACHEDRD2DRD3ALDH1A1KDM4E | |
| SCHEMBL1105716 | 0.81 | ACHE (0.41) | ACHESLC6A5DRD2DRD3DRD4 | |
| SCHEMBL31288161 | 0.79 | DRD2 (0.38) | ACHESLC6A5DRD2DRD3DRD1 | |
| SCHEMBL19893177 | 0.79 | ADORA1 (0.41) | ACHESLC6A5DRD2DRD3SIGMAR1 | |
| SCHEMBL2794854 | 0.77 | CHRM2 (0.46) | ALDH1A1 | |
| SCHEMBL1901800 | 0.76 | MEN1 (0.48) | ALDH1A1 | |
| SCHEMBL8672493 | 0.75 | HTR6 (0.42) | HTR2ADRD2DRD3DRD1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2468743-A1 | Nitrogen-containing bicyclic compounds useful as antibacterial agents | Toyama Chemical Co., Ltd. (JP) | 2012-06-27 | — | — | EP | disclosed |