Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRPF1 | P55201 | 1/20 | 0.54 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11500353 | 0.86 | GAA (0.54) | BRPF1GSK3AGSK3BOPRM1OPRD1 | |
| SCHEMBL17529389 | 0.79 | KMT2A (0.41) | BRPF1GSK3AGSK3BBRD4LMNA | |
| SCHEMBL11455051 | 0.77 | BRPF1 (0.63) | BRPF1GSK3AGSK3BOPRM1OPRD1 | |
| SCHEMBL9698792 | 0.76 | TSHR (0.57) | BRPF1GSK3AGSK3BOPRM1OPRD1 | |
| SCHEMBL10285867 | 0.76 | PDE3B (0.42) | BRPF1BRD4GAALMNAKMT2A | |
| SCHEMBL20578579 | 0.73 | TSHR (0.50) | GSK3AGSK3BGAAABL1LMNA | |
| SCHEMBL3949762 | 0.72 | BRPF1 (0.55) | BRPF1GSK3AGSK3BOPRK1POLB | |
| SCHEMBL8039565 | 0.71 | BRPF1 (0.39) | BRPF1BRD4GAAHSD17B3KMT2A | |
| SCHEMBL14199082 | 0.71 | HTR7 (0.51) | — | |
| SCHEMBL4476006 | 0.70 | BRPF1 (1.00) | BRPF1GSK3AGSK3BOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2468743-A1 | Nitrogen-containing bicyclic compounds useful as antibacterial agents | Toyama Chemical Co., Ltd. (JP) | 2012-06-27 | — | — | EP | disclosed |