Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.42 |
| ▸ | EDNRB | P24530 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5025475 | 0.85 | MEN1 (0.53) | TSHRBRPF1MEN1KMT2AALDH1A1 | |
| SCHEMBL16190011 | 0.80 | TSHR (0.55) | TSHRMEN1KMT2A | |
| SCHEMBL10285253 | 0.76 | BRPF1 (0.54) | BRPF1MEN1KMT2AALDH1A1GSK3A | |
| SCHEMBL11455051 | 0.76 | BRPF1 (0.63) | TSHRBRPF1ALDH1A1GSK3AGSK3B | |
| SCHEMBL8893469 | 0.76 | CA12 (0.40) | MEN1KMT2ACA12CA9 | |
| SCHEMBL7818846 | 0.76 | BRPF1 (0.57) | TSHRBRPF1MEN1KMT2AALDH1A1 | |
| SCHEMBL11500353 | 0.75 | GAA (0.54) | TSHRBRPF1MEN1KMT2AALDH1A1 | |
| SCHEMBL4597653 | 0.74 | TSHR (1.00) | TSHRMEN1KMT2AALDH1A1GSK3A | |
| SCHEMBL8793695 | 0.73 | KMT2A (0.42) | BRPF1MEN1KMT2AALDH1A1CA12 | |
| SCHEMBL31285850 | 0.73 | KMT2A (0.42) | BRPF1MEN1KMT2AALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357307-A1 | CLEAVABLE CYCLIC LOOP NUCLEOTIDES FOR NANOPORE SEQUENCING | ILLUMINA, INC. | 2023-11-09 | — | — | US | disclosed |
| US-20230357307-A1 | CLEAVABLE CYCLIC LOOP NUCLEOTIDES FOR NANOPORE SEQUENCING | ILLUMINA, INC. | 2023-11-09 | — | — | US | disclosed |
| WO-1992005160-A1 | 4-ARYLSULFONYL-3,4-DIHYDRO-2(1H)-QUINOXALINONE-1-ALKANOIC ACIDS, ESTERS, AND SALTS | SARGES REINHARD (US) | 1992-04-02 | — | — | WO | disclosed |
| US-4940708-A | 4-arylsulfonyl-3,4-dihydro-2(1H)-quinoxalinone-1-alkanoic acids, esters, and salts | PFIZER INC. (US) | 1990-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357307-A1 | CLEAVABLE CYCLIC LOOP NUCLEOTIDES FOR NANOPORE SEQUENCING | TENT4A, TENT4B, DNTT | TSHR 3314/4885BRPF1 2825/4885MEN1 953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.