Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 5/20 | 0.42 |
| ▸ | CES2 | O00748 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16246414 | 1.00 | MAPT (0.45) | MAPTCYP2C19CYP3A4L3MBTL1TDP1 | |
| SCHEMBL6209765 | 0.85 | CYP3A4 (0.43) | MAPTCYP2C19CYP3A4L3MBTL1TDP1 | |
| SCHEMBL348321 | 0.84 | AKR1C1 (0.53) | MAPTCYP2C19CYP3A4L3MBTL1TDP1 | |
| SCHEMBL3039305 | 0.84 | AKR1C1 (0.53) | MAPTCYP2C19CYP3A4L3MBTL1TDP1 | |
| SCHEMBL3039302 | 0.84 | AKR1C1 (0.53) | MAPTCYP2C19CYP3A4L3MBTL1TDP1 | |
| SCHEMBL29759324 | 0.83 | NQO2 (0.53) | MAPTCYP2C19CYP3A4TDP1TSHR | |
| SCHEMBL28202429 | 0.82 | TDP1 (0.46) | MAPTCYP2C19CYP3A4L3MBTL1TDP1 | |
| SCHEMBL6971325 | 0.82 | CES1 (0.44) | MAPTCYP2C19CYP3A4L3MBTL1TDP1 | |
| SCHEMBL4755644 | 0.82 | CES2 (0.59) | MAPTCES1CES2AKR1C1CA12 | |
| SCHEMBL14764079 | 0.82 | CES1 (0.48) | MAPTCYP2C19CYP3A4L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10023700-B2 | Hydrogel | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA | 2018-07-17 | — | — | US | disclosed |
| US-20170190844-A1 | HYDROGEL | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2017-07-06 | — | — | US | disclosed |
| US-20110089020-A1 | Continuous Method for Producing Amides of Ethylenically Unsaturated Carboxylic Acids | CLARIANT FINANCE (BVI) LIMITED (VG) | 2011-04-21 | — | — | US | disclosed |
| EP-2274273-A1 | CONTINUOUS METHOD FOR PRODUCING AMIDES OF ETHYLENICALLY UNSATURATED CARBOXYLIC ACIDS | Clariant Finance (BVI) Limited (VG) | 2011-01-19 | — | — | EP | disclosed |
| WO-2009121486-A1 | CONTINUOUS METHOD FOR PRODUCING AMIDES OF ETHYLENICALLY UNSATURATED CARBOXYLIC ACIDS | CLARIANT INTERNATIONAL LTD (CH) | 2009-10-08 | — | — | WO | disclosed |
| US-6696607-B2 | FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2004-02-24 | — | — | US | disclosed |
| US-20030191190-A1 | Use of phenethyl acrylamides, novel phenethyl acrylamides, method for the production thereof and agents containing the same | BASF AKTIENGESELLSCHAFT (DE) | 2003-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190844-A1 | HYDROGEL | CD44, MMP1, COL2A1 | MAPT 4586/4885CYP2C19 3381/4885CYP3A4 3168/4885 |
| US-10023700-B2 | Hydrogel | CD44, MMP1, COL2A1 | MAPT 4586/4885CYP2C19 3381/4885CYP3A4 3168/4885 |
| US-20030191190-A1 | Use of phenethyl acrylamides, novel phenethyl acrylamides, method for the production thereof and agents containing the same | CCR6, CCR3, CCR1 | MAPT 3971/4885CYP2C19 1970/4885CYP3A4 267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.