Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8605565 | 0.76 | TSHR (0.36) | — | |
| SCHEMBL20901160 | 0.76 | — | — | |
| SCHEMBL6783065 | 0.75 | APLNR (0.36) | APLNR | |
| SCHEMBL21118033 | 0.74 | NCF1 (0.30) | — | |
| SCHEMBL21424607 | 0.74 | SIGMAR1 (0.38) | — | |
| SCHEMBL11355958 | 0.73 | NR1H3 (0.31) | — | |
| SCHEMBL19142469 | 0.72 | KDM4E (0.35) | — | |
| SCHEMBL3398441 | 0.71 | APLNR (0.36) | APLNR | |
| SCHEMBL17511761 | 0.71 | ESR2 (0.32) | APLNR | |
| SCHEMBL13742190 | 0.71 | APLNR (0.36) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2202216-B1 | SPIRO-RING COMPOUND AND USE THEREOF FOR MEDICAL PURPOSES | JAPAN TOBACCO INC (JP) | 2012-06-27 | — | — | EP | disclosed |