Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL1962263 | 0.97 | ALDH1A1 (0.31) | ALDH1A1TSHR | |
| SCHEMBL659304 | 0.93 | ALDH1A1 (0.33) | ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL913964 | 0.93 | ALDH1A1 (0.33) | ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL7245917 | 0.87 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL561351 | 0.87 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL229805 | 0.87 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL1100793 | 0.84 | ALDH1A1 (0.33) | ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL3098093 | 0.84 | ALDH1A1 (0.33) | ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL5182814 | 0.82 | SMN1; SMN2 (0.43) | ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL3373378 | 0.80 | SMN1; SMN2 (0.47) | ALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117050608-A | Steel slag-based shield powder coating and preparation method thereof | 安徽工业大学 | 2023-11-14 | — | — | CN | claimed |
| EP-2534132-B1 | SUBSTITUTED PYRROLIDINE-2-CARBOXAMIDES | HOFFMANN LA ROCHE (CH) | 2017-04-26 | — | — | EP | disclosed |
| US-20160201093-A1 | Process for the Bioconversion of C3-C13 Alkanes to C3-C13 Primary Alcohols | BASF SE (DE) | 2016-07-14 | — | — | US | disclosed |
| EP-3027760-A1 | PROCESS FOR THE BIOCONVERSION OF C3-C13 ALKANES TO C3-C 13 PRIMARY ALCOHOLS | BASF SE (DE) | 2016-06-08 | — | — | EP | disclosed |
| WO-2015014644-A1 | PROCESS FOR THE BIOCONVERSION OF C3-C13 ALKANES TO C3-C 13 PRIMARY ALCOHOLS | BASF SE (DE) | 2015-02-05 | — | — | WO | disclosed |
| US-8557754-B2 | Composition of biodegradable gear oil | COUNSEL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2013-10-15 | — | — | US | disclosed |
| US-8354444-B2 | Substituted pyrrolidine-2-carboxamides | HOFFMANN-LA ROCHE INC. (US) | 2013-01-15 | — | — | US | disclosed |
| EP-2534132-A1 | SUBSTITUTED PYRROLIDINE-2-CARBOXAMIDES | F. Hoffmann-La Roche AG (CH) | 2012-12-19 | — | — | EP | disclosed |
| EP-2340021-B1 | SUBSTITUTED PYRROLIDINE-2-CARBOXAMIDES | HOFFMANN LA ROCHE (CH) | 2012-11-07 | — | — | EP | disclosed |
| US-20110207638-A1 | COMPOSITION OF BIODEGRADABLE GEAR OIL | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2011-08-25 | — | — | US | disclosed |
| WO-2011098398-A1 | SUBSTITUTED PYRROLIDINE-2-CARBOXAMIDES | F. HOFFMANN-LA ROCHE AG (CH) | 2011-08-18 | — | — | WO | disclosed |
| EP-2340021-A1 | SUBSTITUTED PYRROLIDINE-2-CARBOXAMIDES | F. Hoffmann-La Roche AG (CH) | 2011-07-06 | — | — | EP | disclosed |
| EP-2274407-A1 | A COMPOSITION OF BIODEGRADABLE GEAR OIL | Council of Scientific & Industrial Research (IN) | 2011-01-19 | — | — | EP | disclosed |
| US-20100152190-A1 | Substituted Pyrrolidine-2-Carboxamides | F. HOFFMANN-LA ROCHE AG (CH) | 2010-06-17 | — | — | US | disclosed |
| WO-2010031713-A1 | SUBSTITUTED PYRROLIDINE-2-CARBOXAMIDES | F. HOFFMANN-LA ROCHE AG (CH) | 2010-03-25 | — | — | WO | disclosed |
| US-20100075948-A1 | Substituted Pyrrolidine-2-Carboxamides | DING QINGJIE | 2010-03-25 | — | — | US | disclosed |
| WO-2009116082-A1 | A COMPOSITION OF BIODEGRADABLE GEAR OIL | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-09-24 | — | — | WO | disclosed |
| US-20090155546-A1 | FILM-FORMING COMPOSITION, METHOD FOR PATTERN FORMATION, AND THREE-DIMENSIONAL MOLD | TOKYO OHKA KOGYO CO., LTD. (JP) | 2009-06-18 | — | — | US | disclosed |
| WO-1993007240-A1 | PROCESS FOR PRODUCING FLUIDS OF ENHANCED THERMAL STABILITY | EXXON CHEMICAL PATENTS INC. (US) | 1993-04-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152190-A1 | Substituted Pyrrolidine-2-Carboxamides | ARG2, CCNY, PYCR1 | ALDH1A1 2027/4885TSHR 846/4885SMN1; SMN2 2109/4885 |
| US-20100075948-A1 | Substituted Pyrrolidine-2-Carboxamides | ARG2, CCNY, PYCR1 | ALDH1A1 2027/4885TSHR 846/4885SMN1; SMN2 2109/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.