SCHEMBL1028645

SCHEMBL1028645

C=CC(CCCCCCCC)C([Sn])(C=C)C=C

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.37
LMNA P02545 1/20 0.34
DNM1 Q05193 2/20 0.33
ADH1B P00325 1/20 0.33
ADH1C P00326 1/20 0.33
ADH1A P07327 1/20 0.33
ADH4 P08319 1/20 0.33
ADH7 P40394 1/20 0.33
OPRM1 P35372 1/20 0.32
THRB P10828 1/20 0.32
FDPS P14324 4/20 0.32
GPR84 Q9NQS5 2/20 0.31
SPHK1 Q9NYA1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1030829 1.00 TSHR (0.37) TSHRLMNADNM1ADH1BADH1C
SCHEMBL1031770 0.92 TSHR (0.32) TSHRDNM1
SCHEMBL27744726 0.77 LMNA (0.43) TSHRLMNADNM1ADH1BADH1C
SCHEMBL11071882 0.77 LMNA (0.43) TSHRLMNADNM1ADH1BADH1C
SCHEMBL28415149 0.76 TSHR (0.37) TSHRLMNADNM1ADH1BADH1C
SCHEMBL8059789 0.76 TSHR (0.37) TSHRLMNADNM1ADH1BADH1C
SCHEMBL8057778 0.76 TSHR (0.37) TSHRLMNADNM1ADH1BADH1C
SCHEMBL8155416 0.73
SCHEMBL11868654 0.72 TSHR (0.36) TSHRLMNADNM1ADH1BADH1C
SCHEMBL9415734 0.72 TSHR (0.37) TSHRLMNADNM1ADH1BADH1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150080581-A1 MULTICOORDINATED METAL COMPLEXES FOR USE IN METATHESIS REACTIONS RIMTEC CORPORATION (JP) 2015-03-19 US disclosed
US-8927670-B2 Multicoordinated metal complexes for use in metathesis reactions RIMTEC CORPORATION (JP) 2015-01-06 US disclosed
EP-2397475-B1 4, 4' disubstituted 4H-cyclopentadithiophene and new methods for synthesising the same IMEC (BE) 2014-11-12 EP disclosed
US-8765882-B2 Polythiophene based active layer for solar cells IMEC (BE) 2014-07-01 US disclosed
US-8450604-B2 Polymerisable compounds for making opto-electronic devices IMEC (BE) 2013-05-28 US disclosed
US-8329923-B2 4, 4′ disubstituted 4H-cyclopentadithiophene and new methods for synthesizing the same IMEC (BE) 2012-12-11 US disclosed
US-20120279569-A1 POLYTHIOPHENE BASED ACTIVE LAYER FOR SOLAR CELLS UNIVERSITEIT HASSELT (BE) 2012-11-08 US disclosed
EP-2509972-A1 POLYMERS COMPRISING 3 -SUBSTITUTED THIOPHENE MOIETIES AS ACTIVE LAYERS FOR SOLAR CELLS IMEC (BE) 2012-10-17 EP disclosed
EP-2307398-B1 POLYMERISABLE COMPOUNDS FOR MAKING OPTO-ELECTRONIC DEVICES IMEC (BE) 2012-09-05 EP disclosed
US-20110313175-A1 4, 4' DISUBSTITUTED 4H-CYCLOPENTADITHIOPHENE AND NEW METHODS FOR SYNTHESISING THE SAME UNIVERSITEIT HASSELT (BE) 2011-12-22 US disclosed
EP-2397475-A1 4, 4' disubstituted 4H-cyclopentadithiophene and new methods for synthesising the same IMEC (BE) 2011-12-21 EP disclosed
WO-2011069554-A1 POLYMERS COMPRISING 3 -SUBSTITUTED THIOPHENE MOIETIES AS ACTIVE LAYERS FOR SOLAR CELLS IMEC (BE) 2011-06-16 WO disclosed
US-20110130522-A1 POLYMERISABLE COMPOUNDS FOR MAKING OPTO-ELECTRONIC DEVICES UNIVERSITEIT HASSELT (BE) 2011-06-02 US disclosed
EP-2307398-A1 POLYMERISABLE COMPOUNDS FOR MAKING OPTO-ELECTRONIC DEVICES IMEC (BE) 2011-04-13 EP disclosed
EP-1757613-B1 Multicoordinated metal complexes for use in metathesis reactions TELENE SAS (FR) 2011-01-19 EP disclosed
WO-2010000504-A1 POLYMERISABLE COMPOUNDS FOR MAKING OPTO-ELECTRONIC DEVICES INTERUNIVERSITAIR MICROELEKTRONICA CENTRUM (BE) 2010-01-07 WO disclosed
US-20080293905-A9 MULTICOORDINATED METAL COMPLEXES FOR USE IN METATHESIS REACTIONS RIMTEC CORPORATION (JP) 2008-11-27 US disclosed
WO-2007022945-A2 MULTICOORDINATED METAL COMPLEXES FOR USE IN METATHESIS REACTIONS VIACATT N.V. (BE) 2007-03-01 WO disclosed
EP-1757613-A1 Multicoordinated metal complexes for use in metathesis reactions Viacatt N.V. (BE) 2007-02-28 EP disclosed
US-20070043188-A1 MULTICOORDINATED METAL COMPLEXES FOR USE IN METATHESIS REACTIONS TELENE S.A.S. (FR) 2007-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150080581-A1 MULTICOORDINATED METAL COMPLEXES FOR USE IN METATHESIS REACTIONS APEX1, SOD1, AP1M1 TSHR 4417/4885LMNA 4135/4885DNM1 82/4885
US-20120279569-A1 POLYTHIOPHENE BASED ACTIVE LAYER FOR SOLAR CELLS SCO2, CLTB, CLTC TSHR 4501/4885LMNA 121/4885DNM1 3784/4885
US-20110313175-A1 4, 4' DISUBSTITUTED 4H-CYCLOPENTADITHIOPHENE AND NEW METHODS FOR SYNTHESISING THE SAME DDT, NISCH, DBH TSHR 784/4885LMNA 3108/4885DNM1 4245/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.