Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 8/20 | 0.36 |
| ▸ | THRA | P10827 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.34 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.34 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.34 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1030669 | 1.00 | EGLN1 (0.36) | EGLN1THRATHRBFFAR4BBOX1 | |
| SCHEMBL523208 | 0.87 | NPSR1 (0.44) | EGLN1THRATHRBRAB9A | |
| SCHEMBL522330 | 0.87 | NPSR1 (0.44) | EGLN1THRATHRBRAB9A | |
| SCHEMBL522331 | 0.87 | NPSR1 (0.44) | EGLN1THRATHRBRAB9A | |
| SCHEMBL1031822 | 0.83 | EGLN1 (0.44) | EGLN1THRATHRBBBOX1FTO | |
| SCHEMBL1032206 | 0.83 | EGLN1 (0.44) | EGLN1THRATHRBBBOX1FTO | |
| SCHEMBL522422 | 0.76 | EGLN1 (0.45) | EGLN1THRATHRBBBOX1FTO | |
| Bicarbonate SCHEMBL1032448 | 0.73 | EGLN1 (0.46) | EGLN1THRATHRBBBOX1FTO | |
| SCHEMBL27762056 | 0.72 | EGLN1 (0.39) | EGLN1THRATHRBBBOX1FTO | |
| SCHEMBL4078672 | 0.72 | ALDH1A1 (0.39) | EGLN1THRATHRBBBOX1FTO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644336-B1 | NITROGEN-CONTAINING HETEROARYL COMPOUNDS AND THEIR USE IN INCREASING ENDOGENEOUS ERYTHROPOIETIN | FIBROGEN INC (US) | 2011-01-19 | — | — | EP | claimed |