Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.44 |
| ▸ | BBOX1 | O75936 | 5/20 | 0.44 |
| ▸ | FTO | Q9C0B1 | 4/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1032206 | 1.00 | EGLN1 (0.44) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL1030669 | 0.83 | EGLN1 (0.36) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL1028657 | 0.83 | EGLN1 (0.36) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL523650 | 0.83 | EGLN1 (0.46) | EGLN1BBOX1FTO | |
| SCHEMBL523649 | 0.83 | EGLN1 (0.46) | EGLN1BBOX1FTO | |
| SCHEMBL523723 | 0.83 | EGLN1 (0.46) | EGLN1BBOX1FTO | |
| SCHEMBL10509618 | 0.73 | SPR (0.46) | FTOHCRTR1HCRTR2 | |
| SCHEMBL2640103 | 0.71 | ALDH1A1 (0.52) | MAPT | |
| SCHEMBL522787 | 0.69 | EGLN1 (0.65) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL522330 | 0.68 | NPSR1 (0.44) | EGLN1THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644336-B1 | NITROGEN-CONTAINING HETEROARYL COMPOUNDS AND THEIR USE IN INCREASING ENDOGENEOUS ERYTHROPOIETIN | FIBROGEN INC (US) | 2011-01-19 | — | — | EP | claimed |