⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6036190 | 0.71 | ALDH1A1 (0.33) | — | |
| SCHEMBL5043501 | 0.70 | DRD2 (0.34) | — | |
| SCHEMBL18760053 | 0.70 | — | — | |
| SCHEMBL41732 | 0.69 | ALDH1A1 (0.35) | — | |
| SCHEMBL1396162 | 0.69 | — | — | |
| SCHEMBL15168859 | 0.69 | — | — | |
| SCHEMBL17644605 | 0.67 | ALDH1A1 (0.32) | — | |
| SCHEMBL1983658 | 0.67 | TSHR (0.32) | — | |
| SCHEMBL1453183 | 0.67 | TSHR (0.36) | — | |
| SCHEMBL9468256 | 0.67 | DAO (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2274310-B1 | FUSED THIOPHENES AND METHODS FOR MAKING AND USING SAME | CORNING INC (US) | 2016-05-25 | — | — | EP | disclosed |
| US-8575354-B1 | Fused thiophenes and methods for making and using same | CORNING INCORPORATED (US) | 2013-11-05 | — | — | US | disclosed |
| US-20130281707-A1 | FUSED THIOPHENES AND METHODS FOR MAKING AND USING SAME | CORNING INC (US) | 2013-10-24 | — | — | US | disclosed |
| US-8487114-B2 | Fused thiophenes and methods for making and using same | CORNING INCORPORATED (US) | 2013-07-16 | — | — | US | disclosed |
| US-20110098478-A1 | FUSED THIOPHENES AND METHODS FOR MAKING AND USING SAME | CORNING INCORPORATED | 2011-04-28 | — | — | US | disclosed |
| EP-2274310-A1 | FUSED THIOPHENES AND METHODS FOR MAKING AND USING SAME | Corning Inc. (US) | 2011-01-19 | — | — | EP | disclosed |
| WO-2009123695-A1 | FUSED THIOPHENES AND METHODS FOR MAKING AND USING SAME | CORNING INCORPORATED (US) | 2009-10-08 | — | — | WO | disclosed |