SCHEMBL5043501

SCHEMBL5043501

CCCC[Sn](CCCC)(CCCC)c1ccsc1

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.34
DRD3 P35462 1/20 0.34
ALDH1A1 P00352 1/20 0.30
TP53 P04637 1/20 0.30
HSP90AA1 P07900 1/20 0.30
CYP3A4 P08684 1/20 0.30
G6PD P11413 1/20 0.30
HPGD P15428 1/20 0.30
ALOX15 P16050 1/20 0.30
TSHR P16473 1/20 0.30
HIF1A Q16665 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1983658 0.75 TSHR (0.32) TP53TSHR
SCHEMBL1028769 0.70
SCHEMBL15648819 0.70 BDKRB2 (0.36) ALDH1A1TP53CYP3A4TSHRHSD17B10
SCHEMBL276811 0.70 LTA4H (0.38) TP53TSHR
SCHEMBL15648671 0.70 BDKRB2 (0.36) ALDH1A1TP53CYP3A4TSHRHSD17B10
SCHEMBL1452840 0.68 HTT (0.38) ALDH1A1CYP3A4G6PDHPGDTSHR
Hydrogen Sulfide SCHEMBL9374535 0.68 DNM1 (0.37) TP53TSHR
SCHEMBL5787759 0.67 MAPT (0.41) DRD3ALDH1A1CYP3A4TSHR
SCHEMBL9901980 0.67 BDKRB2 (0.35)
SCHEMBL1096789 0.67 HTR7 (0.41) HSP90AA1HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119241818-A Wide-band gap conjugated polymer donor material and preparation method and application thereof 青岛大学 2025-01-03 CN claimed
CN-119241818-A Wide-band gap conjugated polymer donor material and preparation method and application thereof 青岛大学 2025-01-03 CN disclosed
EP-1644370-A4 TETRAHYDROQUINOLINE DERIVATIVES AS CANNABINOID RECEPTOR MODULATORS BRISTOL MYERS SQUIBB CO (US) 2008-06-04 EP disclosed
EP-1592698-B1 PHOSPHINE COMPOUND, INTERMEDIATE, PALLADIUM-COMPLEX, AND USE THEREOF TAKASAGO PERFUMERY CO LTD (JP) 2008-03-26 EP disclosed
US-7276608-B2 Tetrahydroquinoline derivatives as cannabinoid receptor modulators BRISTOL-MYERS SQUIBB COMPANY (US) 2007-10-02 US disclosed
US-7144913-B2 Dihydropyrrolo[1,2-a]indole and tetrahydropyrido[1,2-a]-indole derivatives as prostaglandin d2 receptor antagonists MERCK FROSST CANADA & CO. (CA) 2006-12-05 US disclosed
US-7129367-B2 Phosphine compound, its intermediate, its complex with palladium and a manufacturing method of unsaturated compounds by using the palladium complex TAKASAGO INTERNATIONAL CORPORATION (JP) 2006-10-31 US disclosed
US-7129253-B2 Compounds SMITHKLINE BEECHAM CORPORATION (US) 2006-10-31 US disclosed
EP-1395590-B1 DIHYDROPYRROLO¬1,2-A|INDOLE AND TETRAHYDROPYRIDO¬1,2-A|INDOLE DERIVATIVES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS MERCK FROSST CANADA INC (CA) 2006-09-27 EP disclosed
US-7105529-B2 Substituted oxindole derivatives as protein tyrosine and as protein serine/threonine kinase inhibitors and compositions and methods of treating chemotherapy and radiation therapy side effects SMITHKLINE BEECHAM CORPORATION (US) 2006-09-12 US disclosed
EP-0611749-A1 Substituted amic acid derivatives useful for treatment of arteriosclerosis BANYU PHARMACEUTICAL CO., LTD. (JP) 1994-08-24 EP disclosed
US-5324721-A 3-Substituted cephalosporins, and their use as medicaments BAYER AKTIENGESELLSCHAFT (DE) 1994-06-28 US disclosed
US-5306728-A Substituted amine derivatives having antihyperlipemia activity BANYU PHARMACEUTICAL CO., LTD. (JP) 1994-04-26 US disclosed
EP-0587430-A1 Substituted acetamide derivatives for treatment of hypocholesterolaemia, hyperlipaemia and arteriosclerosis BANYU PHARMACEUTICAL CO., LTD. (JP) 1994-03-16 EP disclosed
EP-0567469-A1 14-g(b)-H-, 14- AND 15-EN-11-g(b)-aryl-4-ESTRENES. SCHERING AG (DE) 1993-11-03 EP disclosed
US-5234946-A Anticholesterol, antilipemic BANYU PHARMACEUTICAL CO., LTD. (JP) 1993-08-10 US disclosed
CN-1066271-A 14 β-H-14-and 15-ethylene linkage-11 beta-aryl-4-estrene SCHERING AG (DE) 1992-11-18 CN disclosed
WO-1992011278-A1 14β-H-, 14- AND 15-EN-11β-aryl-4-ESTRENES SCHERING AKTIENGESELLSCHAFT BERLIN UND BERGKAMEN (DE) 1992-07-09 WO disclosed
EP-0448078-A2 Substituted amine derivatives having anti-hyperlipemia activity BANYU PHARMACEUTICAL CO., LTD. (JP) 1991-09-25 EP disclosed
EP-0395768-A1 SUBSTITUTED ALLYLAMINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE BANYU PHARMACEUTICAL CO., LTD. (JP) 1990-11-07 EP disclosed