SCHEMBL102884

SCHEMBL102884

O=[C]c1ccc([C]=O)c(Cl)c1

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 1/20 0.34
MAPK1 P28482 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL95410 0.80 MAPK1 (0.46) MAPK1TDP1
SCHEMBL95434 0.78 TP53 (0.48) MAPK1TDP1
SCHEMBL7171797 0.77
SCHEMBL7241609 0.74 CYP3A4 (0.52) TDP1
SCHEMBL7160560 0.74 HSD17B10 (0.50) MAPK1TDP1
SCHEMBL10348031 0.74 CYP3A4 (0.46)
SCHEMBL2554329 0.74 SLC2A1 (0.43)
SCHEMBL21201454 0.74 IDO1 (0.37) TRPV4MAPK1TDP1
SCHEMBL96822 0.74 CYP11B2 (0.36) TRPV4
SCHEMBL7022727 0.74 ALDH1A1 (0.36) TRPV4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0397160-B1 Process for making fibers with improved hydrolytic stability DU PONT (US) 1996-07-10 EP claimed
EP-0378366-B1 Preparation of 2-chloroterephthaloyl chloride DU PONT (US) 1993-12-08 EP claimed
US-5037596-A Aromatic polyamide containing chloroterephthaloyl chloride E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-08-06 US claimed
US-5003105-A Preparation of 2-chloroterephthaloyl chloride E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-03-26 US claimed
US-5003036-A Tensile strength E. I. DU PONT DE NEMOURS 1991-03-26 US claimed
EP-0397160-A2 Process vor making fibers with improved hydrolytic stability E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-11-14 EP claimed
US-4118232-A Photographic material containing sulphonic acid group containing disazo dyestuffs CIBA-GEIGY AG (CH) 1978-10-03 US claimed
US-9371616-B2 Laminate and production method thereof KONICA MINOLTA HOLDINGS, INC. (JP) 2016-06-21 US disclosed
EP-2802690-B1 METHOD FOR REMOVING SULFUR FROM FIBER USING HALIDE SALT ION EXCHANGE DU PONT (US) 2015-12-09 EP disclosed
EP-2802690-A1 METHOD FOR REMOVING SULFUR FROM FIBER USING HALIDE SALT ION EXCHANGE E. I. Du Pont de Nemours and Company (US) 2014-11-19 EP disclosed
WO-2013105939-A1 METHOD FOR REMOVING SULFUR FROM FIBER USING HALIDE SALT ION EXCHANGE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-07-18 WO disclosed
EP-2426102-A1 PROCESS FOR PRODUCING PHTHALIC ACID COMPOUND INCLUDING CHLORINATED AROMATIC RING Sumitomo Chemical Company, Limited (JP) 2012-03-07 EP disclosed
US-20120035395-A1 PROCESS FOR PRODUCING PHTHALIC ACID COMPOUND INCLUDING CHLORINATED AROMATIC RING SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-09 US disclosed
US-4128559-A ANTIDEPRESSANT EASTMAN KODAK COMPANY (US) 1978-12-05 US disclosed
US-4041011-A FOR POLYMERS EASTMAN KODAK COMPANY (US) 1977-08-09 US disclosed
US-4039502-A DOPES, SULFURIC ACID, FLUOROSULFONIC ACID E. I. DU PONT DE NEMOURS & COMPANY (US) 1977-08-02 US disclosed
US-4035344-A Process for preparing ordered aromatic copolyamide urea polymer THE FIRESTONE TIRE & RUBBER COMPANY (US) 1977-07-12 US disclosed
US-3960818-A Ordered aromatic copolyamide urea polymer THE FIRESTONE TIRE & RUBBER COMPANY (US) 1976-06-01 US disclosed
US-3936418-A Benzotriazole ortho-ester ultraviolet stabilizers and their use in organic compositions EASTMAN KODAK COMPANY (US) 1976-02-03 US disclosed
US-3936478-A Process for the preparation of desmosterol derivatives TEIJIN LIMITED (JA) 1976-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120035395-A1 PROCESS FOR PRODUCING PHTHALIC ACID COMPOUND INCLUDING CHLORINATED AROMATIC RING NISCH, DDT, CUL1 TRPV4 2045/4885MAPK1 3772/4885TDP1 4273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.