Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 19/20 | 0.39 |
| ▸ | LOX | P28300 | 12/20 | 0.39 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12750179 | 0.78 | LOXL2 (0.49) | LOXL2LOXLOXL3HDAC6 | |
| SCHEMBL688303 | 0.74 | LOXL2 (0.44) | LOXL2LOXLOXL3 | |
| SCHEMBL4343502 | 0.69 | LOXL2 (0.56) | LOXL2LOXLOXL3 | |
| SCHEMBL30931700 | 0.68 | LOXL2 (0.62) | LOXL2LOXLOXL3 | |
| Hydrochloric Acid SCHEMBL13570541 | 0.68 | LOXL2 (0.54) | LOXL2LOXLOXL3 | |
| Hydrochloric Acid SCHEMBL30931587 | 0.68 | LOXL2 (0.54) | LOXL2LOXLOXL3 | |
| Hydrochloric Acid SCHEMBL4770701 | 0.67 | LOXL2 (0.57) | LOXL2LOXLOXL3 | |
| SCHEMBL30398543 | 0.66 | LOXL2 (0.59) | LOXL2LOXLOXL3 | |
| SCHEMBL4550458 | 0.66 | LOXL2 (0.59) | LOXL2LOXLOXL3 | |
| SCHEMBL6664243 | 0.66 | LOXL2 (0.59) | LOXL2LOXLOXL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1953148-B1 | HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2012-02-29 | — | — | EP | disclosed |