Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | CASP1 | P29466 | 3/20 | 0.36 |
| ▸ | CASP7 | P55210 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HBB | P68871 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 6/20 | 0.35 |
| ▸ | MAOB | P27338 | 6/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL599885 | 0.78 | TSHR (0.50) | MEN1KMT2AALDH1A1TP53HPGD | |
| SCHEMBL7586133 | 0.76 | MAOA (0.59) | MEN1KMT2AALDH1A1TP53HPGD | |
| SCHEMBL31643666 | 0.76 | MAOA (0.59) | MEN1KMT2AALDH1A1TP53HPGD | |
| SCHEMBL10289767 | 0.74 | CYP2A6 (0.56) | HPGDTSHRL3MBTL1MAOAMAOB | |
| SCHEMBL7166999 | 0.73 | TSHR (0.46) | MEN1KMT2AALDH1A1TP53HPGD | |
| SCHEMBL29807605 | 0.73 | TSHR (0.58) | MEN1KMT2AALDH1A1HPGDTSHR | |
| SCHEMBL322056 | 0.73 | TSHR (0.58) | MEN1KMT2AALDH1A1HPGDTSHR | |
| SCHEMBL19810100 | 0.69 | TSHR (0.52) | MEN1KMT2AALDH1A1HPGDCASP1 | |
| SCHEMBL4541419 | 0.69 | TSHR (0.52) | MEN1KMT2AALDH1A1HPGDCASP1 | |
| SCHEMBL5491066 | 0.69 | TSHR (0.52) | MEN1KMT2AALDH1A1HPGDCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0470127-B1 | PCP RECEPTOR LIGANDS AND THE USE THEREOF | OREGON STATE (US) | 2003-02-26 | — | — | EP | disclosed |
| US-6017910-A | PCP receptor ligands and the use thereof | STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION ACTING FOR AND ON BEHALF OF THE OREGON HEALTH SCIENCES UNIVERSITY AND THE UNIVERSITY OF OREGON (US) | 2000-01-25 | — | — | US | disclosed |
| US-5688789-A | TREATMENT OR PREVENTION OF NEURONAL LOSS IN ISCHEMIA, HYPOXIA, BRAIN OR SPINAL CORD TRAUMA, TREATMENT OF ALZHEIMER'S DISEASE, AMYOTROPHIC LATERAL SCLEROSIS, HUNTINGTON'S DISEASE, DOWN'S SYNDROME | STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION, ACTING FOR AND ON BEHALF OF THE OREGON HEALTH SCIENCES UNIVERSITY AND THE UNIVERSITY OF OREGON (US) | 1997-11-18 | — | — | US | disclosed |
| EP-0587670-A4 | PCP RECEPTOR LIGANDS AND THE USE THEREOF. | OREGON STATE (US) | 1995-02-01 | — | — | EP | disclosed |
| EP-0587670-A1 | PCP RECEPTOR LIGANDS AND THE USE THEREOF | STATE OF OREGON, acting through OREGON STATE BOARD OF HIGHER EDUCATION, acting for OREGON HEALTH SC. UNIV. AND UNIV. OF OREGON (US) | 1994-03-23 | — | — | EP | disclosed |
| WO-1992019621-A1 | PCP RECEPTOR LIGANDS AND THE USE THEREOF | STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION, ACTING FOR AND ON BEHALF OF THE OREGON HEALTH SCIENCES UNIVERSITY AND THE UNIVERSITY OF OREGON, EUGENE, OREGON (US) | 1992-11-12 | — | — | WO | disclosed |
| EP-0470127-A4 | PCP RECEPTOR LIGANDS AND THE USE THEREOF | — | 1992-06-24 | — | — | EP | disclosed |
| EP-0470127-A1 | PCP RECEPTOR LIGANDS AND THE USE THEREOF | STATE OF OREGON BY AND THROUGH OREGON STATE BOARD OF HIGHER EDUCATION ON BEHALF OREGON HEALTH SC. UNIV. AND OREGON STATE UNIV. (US) | 1992-02-12 | — | — | EP | disclosed |
| US-5011834-A | Treating or preventing neuronal loss in ischemia, hypoxia, brain and spinal cord trauma, Alzheimer*s | STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION, ACTING FOR AND ON BEHALF OF THE OREGON HEALTH SCIENCES UNIVERSITY AND THE UNIVERSITY OF OREGON (US) | 1991-04-30 | — | — | US | disclosed |
| WO-1990012575-A1 | PCP RECEPTOR LIGANDS AND THE USE THEREOF | STATE OF OREGON, ACTING BY AND THROUGH THE OREGON STATE BOARD OF HIGHER EDUCATION, ACTING FOR AND ON BEHALF OF THE OREGON HEALTH SCIENCES UNIVERSITY AND THE UNIVERSITY OF OREGON (US) | 1990-11-01 | — | — | WO | disclosed |
| US-4052508-A | TRANQUILIZER, MUSCLE RELAXANT, ANTICONVULSANT, ANTIPARKINSON | MERCK & CO., INC. (US) | 1977-10-04 | — | — | US | disclosed |
| US-4052508-A | TRANQUILIZER, MUSCLE RELAXANT, ANTICONVULSANT, ANTIPARKINSON | MERCK & CO., INC. (US) | 1977-10-04 | — | — | US | disclosed |