Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | OGG1 | O15527 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1027999 | 0.87 | HSD17B3 (0.41) | LMNANPC1CYP1A2RAB9ACYP2C19 | |
| SCHEMBL1026097 | 0.87 | CYP1A2 (0.40) | LMNANPC1CYP1A2RAB9ACYP2C19 | |
| SCHEMBL1023783 | 0.86 | OGG1 (0.54) | LMNANPC1CYP1A2RAB9ACYP2C19 | |
| SCHEMBL1025805 | 0.77 | SMN1; SMN2 (0.46) | LMNACYP1A2RAB9ACYP2C19AGTR1 | |
| SCHEMBL1027198 | 0.75 | MAPT (0.45) | LMNANPC1CYP1A2RAB9ACYP2C19 | |
| SCHEMBL1026536 | 0.73 | NAAA (0.45) | LMNANPC1CYP1A2RAB9ACYP2C19 | |
| SCHEMBL1026088 | 0.72 | NPC1 (0.56) | LMNANPC1CYP1A2RAB9ACYP2C19 | |
| SCHEMBL1025204 | 0.72 | MAPT (0.47) | LMNANPC1CYP1A2RAB9ACYP2C19 | |
| SCHEMBL3966650 | 0.71 | LMNA (0.56) | LMNANPC1CYP1A2RAB9ACYP2C19 | |
| SCHEMBL1027788 | 0.71 | LMNA (0.43) | LMNANPC1CYP1A2RAB9ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1608623-B1 | METAL ION CHELATORS AND THERAPEUTIC USE THEREOF | RICHARDSON DESI RAYMOND (AU) | 2011-01-19 | — | — | EP | claimed |