Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | AGXT | P21549 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | AOC2 | O75106 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19360595 | 0.78 | EPHX1 (0.50) | CPA1TAAR1MAOA | |
| SCHEMBL8693276 | 0.78 | TRPA1 (0.44) | TRPA1IDO1LOXL2CPA1TAAR1 | |
| SCHEMBL12226226 | 0.75 | TRPA1 (0.46) | TRPA1IDO1LOXL2CPA1LMNA | |
| SCHEMBL21439149 | 0.75 | TP53 (0.61) | TRPA1IDO1LOXL2CPA1TAAR1 | |
| SCHEMBL4011260 | 0.75 | TRPA1 (0.41) | TRPA1IDO1LOXL2CPA1TAAR1 | |
| SCHEMBL204959 | 0.75 | TP53 (0.61) | TRPA1IDO1LOXL2CPA1TAAR1 | |
| SCHEMBL754753 | 0.75 | TRPA1 (0.41) | TRPA1IDO1LOXL2CPA1TAAR1 | |
| SCHEMBL2269305 | 0.75 | LOXL2 (0.43) | TRPA1IDO1LOXL2CPA1TAAR1 | |
| SCHEMBL12809801 | 0.75 | LOXL2 (0.43) | TRPA1IDO1LOXL2CPA1TAAR1 | |
| SCHEMBL2268274 | 0.75 | LOXL2 (0.43) | TRPA1IDO1LOXL2CPA1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1422218-B1 | ANTIVIRAL AGENT | SHIONOGI & CO (JP) | 2012-03-21 | — | — | EP | disclosed |