SCHEMBL10291406

SCHEMBL10291406

CCCCOCC1O[C@@H](O[C@@H]2C(COCCCC)O[C@@H](O)C(OCCCC)C2OCCCC)C(OCCCC)C(OCCCC)[C@H]1O

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ GJB2 P29033 5/20 0.48
▸ TNF P01375 1/20 0.41
▸ GBA1 P04062 1/20 0.37
▸ HPSE Q9Y251 6/20 0.34
▸ FGF1 P05230 6/20 0.34
▸ FGF2 P09038 5/20 0.34
▸ VEGFA P15692 3/20 0.34
▸ SSTR1 P30872 1/20 0.34
▸ SSTR2 P30874 1/20 0.34
▸ SSTR4 P31391 1/20 0.34
▸ SSTR3 P32745 1/20 0.34
▸ SSTR5 P35346 1/20 0.34
▸ SLC2A1 P11166 1/20 0.32
▸ TACR1 P25103 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15883868 1.00 GJB2 (0.48) GJB2TNFGBA1HPSEFGF1
SCHEMBL12898703 0.94 GJB2 (0.46) GJB2TNFGBA1FGF1SLC2A1
SCHEMBL10291407 0.94 GJB2 (0.50) GJB2TNFGBA1HPSEFGF1
SCHEMBL18315050 0.94 GJB2 (0.50) GJB2TNFGBA1HPSEFGF1
SCHEMBL10292101 0.94 GJB2 (0.48) GJB2TNFGBA1HPSEFGF1
SCHEMBL19204221 0.94 GJB2 (0.48) GJB2TNFGBA1HPSEFGF1
SCHEMBL19204198 0.91 GJB2 (0.52) GJB2TNFGBA1HPSEFGF1
SCHEMBL19277314 0.90 GJB2 (0.48) GJB2TNFGBA1HPSEFGF1
SCHEMBL18311512 0.90 GJB2 (0.49) GJB2TNFGBA1HPSEFGF1
SCHEMBL18311516 0.88 GJB2 (0.49) GJB2TNFGBA1HPSEFGF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120277172-A1 CARBOHYDRATE-LIPID CONSTRUCTS AND THEIR USE IN PREVENTING OR TREATING VIRAL INFECTION KODE BIOTECH LIMITED (NZ) 2012-11-01 — — US disclosed
US-8211860-B2 Carbohydrate-lipid constructs and their use in preventing or treating viral infection KODE BIOTECH LIMITED (NZ) 2012-07-03 — — US disclosed
US-20100184723-A1 CARBOHYDRATE-LIPID CONSTRUCTS AND THEIR USE IN PREVENTING OR TREATING VIRAL INFECTION KODE BIOTECH LIMITED (NZ) 2010-07-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100184723-A1 CARBOHYDRATE-LIPID CONSTRUCTS AND THEIR USE IN PREVENTING OR TREATING VIRAL INFECTION HAVCR2, SIGLEC7, CD14 GJB2 4066/4885TNF 1339/4885GBA1 162/4885
US-20120277172-A1 CARBOHYDRATE-LIPID CONSTRUCTS AND THEIR USE IN PREVENTING OR TREATING VIRAL INFECTION HAVCR2, SIGLEC7, FUT5 GJB2 3919/4885TNF 1402/4885GBA1 155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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