Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | GAA | P10253 | 4/20 | 0.58 |
| ▸ | PKM | P14618 | 3/20 | 0.58 |
| ▸ | KHK | P50053 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29353981 | 1.00 | NPSR1 (1.00) | NPSR1ALDH1A1KDM4EMAPTGAA | |
| Pyrrolidine SCHEMBL4724716 | 0.88 | NPSR1 (0.77) | NPSR1ALDH1A1KDM4EMAPTGAA | |
| Diphenylether SCHEMBL4184182 | 0.88 | NPSR1 (0.77) | NPSR1ALDH1A1KDM4EMAPTGAA | |
| SCHEMBL4374246 | 0.88 | NPSR1 (0.78) | NPSR1ALDH1A1KDM4EMAPTGAA | |
| SCHEMBL9960528 | 0.86 | NPSR1 (0.75) | NPSR1ALDH1A1KDM4EMAPTGAA | |
| SCHEMBL23854433 | 0.84 | NPSR1 (0.72) | NPSR1ALDH1A1KDM4EMAPTGAA | |
| SCHEMBL5015526 | 0.84 | NPSR1 (0.72) | NPSR1ALDH1A1KDM4EMAPTGAA | |
| SCHEMBL7532421 | 0.84 | NPSR1 (0.72) | NPSR1ALDH1A1KDM4EMAPTGAA | |
| SCHEMBL13049405 | 0.84 | NPSR1 (0.72) | NPSR1ALDH1A1KDM4EMAPTGAA | |
| SCHEMBL7532738 | 0.84 | NPSR1 (0.72) | NPSR1ALDH1A1KDM4EMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 431 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120157621-A | Method for synthesizing acetamide compound through visible light induced defluorination coupling | 南京工业大学 | 2025-06-17 | — | — | CN | claimed |
| CN-119425419-A | Metal-organic framework composite membrane for helium and methane mixed gas separation and preparation method and application thereof | 苏州大学 | 2025-02-14 | — | — | CN | claimed |
| CN-114573512-B | Method for synthesizing C2-difluoro alkyl benzimidazole derivative | 徐州医科大学 | 2024-02-23 | — | — | CN | claimed |
| CN-117534620-A | Preparation method of palladium-catalyzed hydrocarbon bond functionalized 2-trifluoromethyl benzimidazole compound | 六盘水师范学院 | 2024-02-09 | — | — | CN | claimed |
| CN-117285985-A | Low-dynamic surface tension insulating layer buffer cleaning liquid and preparation method and application thereof | 四川格林达电子材料有限公司 | 2023-12-26 | — | — | CN | claimed |
| CN-116715672-A | Trifluoromethyl modified macrocyclic supermolecule main body molecular cup and metal molecular cup, and preparation methods and applications thereof | 上海大学 | 2023-09-08 | — | — | CN | claimed |
| CN-115945180-A | Adsorbent for refining hexafluoro-1, 3-butadiene and preparation method and application thereof | 天津绿菱气体有限公司 | 2023-04-11 | — | — | CN | claimed |
| CN-112581856-B | Temperature indicating label | 苏州和萃新材料有限公司 | 2022-07-19 | — | — | CN | claimed |
| CN-114573512-A | Method for synthesizing C2-difluoroalkyl benzimidazole derivative | 徐州医科大学 | 2022-06-03 | — | — | CN | claimed |
| CN-113789086-A | High-temperature color-changing ink and label | 江苏集萃智能液晶科技有限公司 | 2021-12-14 | — | — | CN | claimed |
| EP-1551811-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS VANILLOID RECEPTOR LIGANDS | Amgen Inc. (US) | 2005-07-13 | — | — | EP | claimed |
| WO-2004035549-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS VANILLOID RECEPTOR LIGANDS | AMGEN INC. (US) | 2004-04-29 | — | — | WO | claimed |
| EP-0596358-B1 | 0-Phenylenediamines containing fluoroakyl(ene) groups and their use as intermediates in the preparation of benzimidazoles | BAYER AG (DE) | 1998-10-28 | — | — | EP | claimed |
| EP-0596358-A1 | 0-Phenylenediamines containing fluoroakyl(ene) groups and their use as intermediates in the preparation of benzimidazoles | BAYER AG (DE) | 1994-05-11 | — | — | EP | claimed |
| EP-0251014-B1 | 2-TRIFLUOROMETHYL BENZIMIDAZOLES | BAYER AG (DE) | 1992-05-20 | — | — | EP | claimed |
| US-4767444-A | Herbicidal and microbiocidal 2-trifluoromethyl-benzimidazoles | BAYER AKTIENGESELLSCHAFT (DE) | 1988-08-30 | — | — | US | claimed |
| EP-0251014-A2 | 2-Trifluoromethyl benzimidazoles | BAYER AG (DE) | 1988-01-07 | — | — | EP | claimed |
| EP-0251012-A2 | N-sulfenyl-2-trifluoromethyl benzimidazoles | BAYER AG (DE) | 1988-01-07 | — | — | EP | claimed |
| EP-0239508-A2 | 2-Cyano-benzimidazole derivatives, their preparation and use as fungicides, their association with other fungicides | RHONE-POULENC AGROCHIMIE (FR) | 1987-09-30 | — | — | EP | claimed |
| US-3987181-A | CERTAIN 2-TRIFLUOROMETHYLBENZIMIDAZOLES AS ANTHELMINTICS | CIBA-GEIGY CORPORATION (US) | 1976-10-19 | — | — | US | claimed |