Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | PKM | P14618 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | KHK | P50053 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MASP2 | O00187 | 1/20 | 0.47 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.47 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29961428 | 0.93 | NPSR1 (0.68) | NPSR1ALDH1A1POLBKDM4ENPC1 | |
| SCHEMBL28666603 | 0.93 | NPSR1 (0.68) | NPSR1ALDH1A1POLBKDM4ENPC1 | |
| SCHEMBL4374246 | 0.92 | NPSR1 (0.78) | NPSR1ALDH1A1POLBKDM4ENPC1 | |
| Bromide SCHEMBL10525679 | 0.91 | NPSR1 (0.66) | NPSR1ALDH1A1POLBKDM4ENPC1 | |
| SCHEMBL5015526 | 0.89 | NPSR1 (0.72) | NPSR1ALDH1A1POLBKDM4ENPC1 | |
| SCHEMBL29353981 | 0.84 | NPSR1 (1.00) | NPSR1ALDH1A1POLBKDM4ENPC1 | |
| SCHEMBL10295 | 0.84 | NPSR1 (1.00) | NPSR1ALDH1A1POLBKDM4ENPC1 | |
| SCHEMBL9960528 | 0.82 | NPSR1 (0.75) | NPSR1ALDH1A1POLBKDM4ENPC1 | |
| SCHEMBL7532421 | 0.81 | NPSR1 (0.72) | NPSR1ALDH1A1POLBKDM4ENPC1 | |
| SCHEMBL13049405 | 0.81 | NPSR1 (0.72) | NPSR1ALDH1A1POLBKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11912825-B2 | Polymers derived from 2,2′-bisimidazoles | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2024-02-27 | — | — | US | disclosed |
| US-11912825-B2 | Polymers derived from 2,2′-bisimidazoles | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) | 2024-02-27 | — | — | US | disclosed |
| US-20210301085-A1 | POLYMERS DERIVED FROM 2,2'-BISIMIDAZOLES | UNITED STATES DEPARTMENT OF ENERGY | 2021-09-30 | — | — | US | disclosed |
| US-20210301085-A1 | POLYMERS DERIVED FROM 2,2'-BISIMIDAZOLES | UNITED STATES DEPARTMENT OF ENERGY | 2021-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210301085-A1 | POLYMERS DERIVED FROM 2,2'-BISIMIDAZOLES | PARG, PARN, NOP2 | NPSR1 4417/4885ALDH1A1 2034/4885POLB 22/4885 |
| US-11912825-B2 | Polymers derived from 2,2′-bisimidazoles | PARG, PARN, NOP2 | NPSR1 4409/4885ALDH1A1 2052/4885POLB 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.