Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | PKM | P14618 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | KHK | P50053 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | MASP2 | O00187 | 1/20 | 0.50 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23854433 | 0.92 | NPSR1 (0.72) | NPSR1ALDH1A1POLBKDM4ENPC1 | |
| SCHEMBL5015526 | 0.92 | NPSR1 (0.72) | NPSR1ALDH1A1POLBKDM4ENPC1 | |
| SCHEMBL28666603 | 0.89 | NPSR1 (0.68) | NPSR1ALDH1A1POLBKDM4ENPC1 | |
| SCHEMBL29961428 | 0.89 | NPSR1 (0.68) | NPSR1ALDH1A1POLBKDM4ENPC1 | |
| SCHEMBL29353981 | 0.88 | NPSR1 (1.00) | NPSR1ALDH1A1POLBKDM4ENPC1 | |
| SCHEMBL10295 | 0.88 | NPSR1 (1.00) | NPSR1ALDH1A1POLBKDM4ENPC1 | |
| Bromide SCHEMBL10525679 | 0.87 | NPSR1 (0.66) | NPSR1ALDH1A1POLBKDM4ENPC1 | |
| SCHEMBL9960528 | 0.86 | NPSR1 (0.75) | NPSR1ALDH1A1POLBKDM4ENPC1 | |
| SCHEMBL7532421 | 0.84 | NPSR1 (0.72) | NPSR1ALDH1A1POLBKDM4ENPC1 | |
| SCHEMBL13049405 | 0.84 | NPSR1 (0.72) | NPSR1ALDH1A1POLBKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7498390-B2 | Chromium complexes and their use in olefin polymerization | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2009-03-03 | — | — | US | disclosed |
| US-7498287-B2 | Chromium complexes and their use in olefin polymerization | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2009-03-03 | — | — | US | disclosed |
| US-20080071090-A1 | Chromium complexes and their use in olefin polymerization | KACKER SMITA | 2008-03-20 | — | — | US | disclosed |
| US-20080021181-A1 | Chromium complexes and their use in olefin polymerization | KACKER SMITA | 2008-01-24 | — | — | US | disclosed |
| US-7297805-B2 | Chromium complexes and their use in olefin polymerization | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2007-11-20 | — | — | US | disclosed |
| EP-1789425-A2 | CHROMIUM COMPLEXES AND THEIR USE IN OLEFIN POLYMERIZATION | ExxonMobil Research and Engineering Company (US) | 2007-05-30 | — | — | EP | disclosed |
| WO-2006012327-A2 | CHROMIUM COMPLEXES AND THEIR USE IN OLEFIN POLYMERIZATION | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2006-02-02 | — | — | WO | disclosed |
| US-20050288464-A1 | Chromium complexes and their use in olefin polymerization | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288464-A1 | Chromium complexes and their use in olefin polymerization | CBR3, CDYL, CCRL2 | NPSR1 1700/4885ALDH1A1 4541/4885POLB 1555/4885 |
| US-20080071090-A1 | Chromium complexes and their use in olefin polymerization | CBR3, CDYL, CCRL2 | NPSR1 1700/4885ALDH1A1 4541/4885POLB 1555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.