Pyridine

Pyridine

SCHEMBL1029574

CC(C)O.c1ccncc1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.60
NAPRT Q6XQN6 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.36
GAA P10253 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
KDM4E B2RXH2 2/20 0.31
HSD17B10 Q99714 1/20 0.31
NOTUM Q6P988 1/20 0.30
TP53 P04637 1/20 0.30
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL11827089 1.00 TSHR (0.60) TSHRNAPRTTDP1ALDH1A1LMNA
Pyridine SCHEMBL28189164 0.97 TSHR (0.56) TSHRNAPRTTDP1ALDH1A1LMNA
Pyridine SCHEMBL28227097 0.97 TSHR (0.56) TSHRNAPRTTDP1ALDH1A1LMNA
Pyridine SCHEMBL28101857 0.97 TSHR (0.56) TSHRNAPRTTDP1ALDH1A1LMNA
Pyridine SCHEMBL11324194 0.97 TSHR (0.56) TSHRNAPRTTDP1ALDH1A1LMNA
Pyridine SCHEMBL5512081 0.89 NAPRT (0.47) TSHRNAPRTTDP1ALDH1A1LMNA
Pyridine SCHEMBL645634 0.89 TSHR (0.47) TSHRNAPRTTDP1ALDH1A1LMNA
Pyridine SCHEMBL28351603 0.88 TSHR (0.53) TSHRNAPRTTDP1SMN1; SMN2GAA
Pyridine SCHEMBL5358027 0.87 NAPRT (0.45) TSHRNAPRTTDP1ALDH1A1GAA
Pyridine SCHEMBL28360582 0.87 TSHR (0.45) TSHRNAPRTTDP1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110446706-A (S)-[the fluoro- 5- of the chloro- 4- of 2- (7- morpholine -4- base quinazoline -4- base) phenyl] crystal form of-(6- methoxy-pyridazine -3- base) methanol MERCK PATENT GMBH 2019-11-12 CN claimed
CN-109111714-A Silver nanowires modified fullerenes micro/nano-fibre, preparation method and applications 四川龙华光电薄膜股份有限公司 2019-01-01 CN claimed
CN-108559111-A The preparation method of strong adhesive force fullerene micro/nano-fibre antistatic film 四川龙华光电薄膜股份有限公司 2018-09-21 CN claimed
CN-116180133-A Nickel-based metal organic framework/graphite felt electrode material and preparation method and application thereof 浙江工业大学 2023-05-30 CN disclosed
US-11186545-B2 Phenalene-1-one-containing photosensitizer composition, phenalene-1-one compound and the use thereof TRIOPTOTEC GMBH (DE) 2021-11-30 US disclosed
US-20200087259-A1 PHENALENE-1-ONE-CONTAINING PHOTOSENSITIZER COMPOSITION, PHENALENE-1-ONE COMPOUND AND THE USE THEREOF TRIOPTOTEC GMBH (DE) 2020-03-19 US disclosed
CN-110446706-A (S)-[the fluoro- 5- of the chloro- 4- of 2- (7- morpholine -4- base quinazoline -4- base) phenyl] crystal form of-(6- methoxy-pyridazine -3- base) methanol MERCK PATENT GMBH 2019-11-12 CN disclosed
CN-107207532-B Nitroimidazole derivatives against tuberculosis 南京明德新药研发股份有限公司 2019-07-30 CN disclosed
CN-106634938-B Composite temperature-resistant viscoelastic self-diverting acid and preparation method and application thereof 中国石油天然气股份有限公司 2019-07-09 CN disclosed
CN-109111714-A Silver nanowires modified fullerenes micro/nano-fibre, preparation method and applications 四川龙华光电薄膜股份有限公司 2019-01-01 CN disclosed
CN-108559111-A The preparation method of strong adhesive force fullerene micro/nano-fibre antistatic film 四川龙华光电薄膜股份有限公司 2018-09-21 CN disclosed
EP-0146785-B1 PROCESS FOR THE PREPARATION OF PROTEASE INHIBITORS CIBA-GEIGY AG (CH) 1990-02-07 EP disclosed
US-4868336-A CATALYTIC OXIDATION OF MERCAPTAN PHILLIPS PETROLEUM COMPANY (US) 1989-09-19 US disclosed
EP-0316942-A2 Manufacture of disulfides PHILLIPS PETROLEUM COMPANY (US) 1989-05-24 EP disclosed
EP-0188400-A2 Oligopeptides, intermediates and process for their preparation CIBA-GEIGY AG (CH) 1986-07-23 EP disclosed
EP-0168342-A1 Process for the preparation of thrombin inhibitors CIBA-GEIGY AG (CH) 1986-01-15 EP disclosed
EP-0146785-A1 Process for the preparation of protease inhibitors CIBA-GEIGY AG (CH) 1985-07-03 EP disclosed
US-RE31664-E THICKENER, GELLING AGENT IDEMITSU KOSAN COMPANY LIMITED (JP) 1984-09-04 US disclosed
US-4153508-A CULTURING ARTHROBACTERIA IN ASSIMILABLE CARBON AND NITROGEN SOURCES IDEMITSU KOSAN COMPANY LIMITED (JP) 1979-05-08 US disclosed
US-4146706-A GEL-FORMING IDEMITSU KOSAN COMPANY LIMITED (JP) 1979-03-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200087259-A1 PHENALENE-1-ONE-CONTAINING PHOTOSENSITIZER COMPOSITION, PHENALENE-1-ONE COMPOUND AND THE USE THEREOF PYCR1, CRY1, PPOX TSHR 4876/4885NAPRT 2580/4885TDP1 886/4885
US-11186545-B2 Phenalene-1-one-containing photosensitizer composition, phenalene-1-one compound and the use thereof PYCR1, CRY1, PPOX TSHR 4876/4885NAPRT 2580/4885TDP1 886/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.