Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.35 |
| ▸ | HTR3B | O95264 | 2/20 | 0.35 |
| ▸ | HTR3A | P46098 | 2/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4403176 | 0.84 | ACHE (0.44) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL20198346 | 0.76 | ALOX12 (0.43) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL821944 | 0.76 | MAPT (0.39) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL12309398 | 0.76 | MAPT (0.39) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL677862 | 0.76 | MAPT (0.39) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL12761442 | 0.74 | MAPT (0.38) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL17228771 | 0.74 | ACHE (0.56) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL14227572 | 0.74 | HPGD (0.39) | MAPTL3MBTL1TDP1HPGD | |
| SCHEMBL14594146 | 0.72 | HPGD (0.50) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL13695284 | 0.71 | MAPT (0.36) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150166345-A1 | ELECTROCHEMICAL SENSORS | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2015-06-18 | — | — | US | disclosed |
| US-8961754-B2 | Electrochemical sensors | ISIS INNOVATION LTD (GB) | 2015-02-24 | — | — | US | disclosed |
| US-8562797-B2 | Electrochemical sensors | ISIS INNOVATION LIMITED (GB) | 2013-10-22 | — | — | US | disclosed |
| US-20120168308-A1 | ELECTROCHEMICAL SENSORS | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2012-07-05 | — | — | US | disclosed |
| US-20080035481-A1 | Electrochemical Sensors | HARRIS & HARRIS GROUP, INC. | 2008-02-14 | — | — | US | disclosed |