Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX12 | P18054 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HK1 | P19367 | 1/20 | 0.39 |
| ▸ | MPI | P34949 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4403176 | 0.91 | ACHE (0.44) | ALOX12ACHELMNACYP2D6MAPT | |
| SCHEMBL755432 | 0.85 | ALDH1A1 (0.47) | LMNATSHRMAPTALDH1A1MAPK1 | |
| SCHEMBL821944 | 0.82 | MAPT (0.39) | ALOX12ACHELMNACYP2D6MAPT | |
| SCHEMBL677862 | 0.82 | MAPT (0.39) | ALOX12ACHELMNACYP2D6MAPT | |
| SCHEMBL12309398 | 0.82 | MAPT (0.39) | ALOX12ACHELMNACYP2D6MAPT | |
| SCHEMBL20683979 | 0.82 | ALDH1A1 (0.36) | LMNATSHRMAPTALDH1A1MAPK1 | |
| SCHEMBL17228771 | 0.80 | ACHE (0.56) | ALOX12ACHELMNAMAPTALDH1A1 | |
| SCHEMBL12761442 | 0.80 | MAPT (0.38) | ALOX12ACHELMNACYP2D6MAPT | |
| SCHEMBL6208251 | 0.79 | ALDH1A1 (0.38) | LMNATSHRMAPTALDH1A1MAPK1 | |
| SCHEMBL14594146 | 0.78 | HPGD (0.50) | ALOX12LMNATSHRCYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675930-B1 | NEW MATERIALS FOR ELECTROLUMINESCENCE AND THE UTILIZATION THEREOF | MERCK PATENT GMBH (DE) | 2018-05-30 | — | — | EP | disclosed |