SCHEMBL102964

SCHEMBL102964

Fc1cc2nn[nH]c2cc1F

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
HPGD P15428 1/20 0.35
CYP2C19 P33261 1/20 0.35
HSD17B10 Q99714 1/20 0.35
CYP11B2 P19099 1/20 0.33
CBFB Q13951 1/20 0.33
GPR84 Q9NQS5 1/20 0.32
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12121753 0.85 DAO (0.36)
SCHEMBL14730924 0.85
SCHEMBL25247956 0.83 ILK (0.33)
SCHEMBL2589396 0.83 EGLN1 (0.34)
SCHEMBL28695956 0.83 MAPT (0.43) ALDH1A1GPR84MAPT
SCHEMBL26449991 0.83 DAO (0.35) KDM4EMAPT
SCHEMBL8568181 0.83 MAPT (0.52) ALDH1A1GPR84MAPT
SCHEMBL12180644 0.83 MAPT (0.35) KDM4EALDH1A1CYP2C9CYP2C19HSD17B10
SCHEMBL2705071 0.79
SCHEMBL23845783 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120035304-A Perovskite solar cell and crystal surface defect passivation method thereof 中国长江三峡集团有限公司 2025-05-23 CN claimed
CN-119241454-A Fluorescent material of 5, 6-difluoro benzotriazoles derivative and application thereof 南京欧纳壹有机光电有限公司 2025-01-03 CN claimed
WO-2025264724-A1 MPRO INHIBITORS AND USES THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2025-12-26 WO disclosed
EP-4660199-A1 19-NOR NEUROACTIVE STEROIDS FOR INDUCING SEDATION Sage Therapeutics, Inc. (US) 2025-12-10 EP disclosed
CN-120035304-A Perovskite solar cell and crystal surface defect passivation method thereof 中国长江三峡集团有限公司 2025-05-23 CN disclosed
CN-116041672-B Polymer based on 4-alkylthio thiophene/4-alkylseleno thiophene, preparation method and application 南方科技大学 2025-05-09 CN disclosed
CN-119241454-A Fluorescent material of 5, 6-difluoro benzotriazoles derivative and application thereof 南京欧纳壹有机光电有限公司 2025-01-03 CN disclosed
CN-119241454-A Fluorescent material of 5, 6-difluoro benzotriazoles derivative and application thereof 南京欧纳壹有机光电有限公司 2025-01-03 CN disclosed
EP-3719030-B1 19-NOR NEUROACTIVE STEROIDS FOR INDUCING SEDATION SAGE THERAPEUTICS INC (US) 2024-07-10 EP disclosed
CN-117304245-A 19-nor steroids that stimulate neural activity and methods of use thereof 萨奇治疗股份有限公司 2023-12-29 CN disclosed
CN-112110976-B 19-nor steroids that stimulate neural activity and methods of use thereof 萨奇治疗股份有限公司 2023-08-29 CN disclosed
US-20130092912-A1 POLYMERS WITH TUNABLE BAND GAPS FOR PHOTONIC AND ELECTRONIC APPLICATIONS NAVY, SECRETARY OF THE UNITED STATES OF AMERICA 2013-04-18 US disclosed
US-20120319097-A1 ELECTRODE TREATMENT PROCESS FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2012-12-20 US disclosed
US-20120277237-A1 NOVEL ALKYNYL DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS ADDEX PHARMA SA (CH) 2012-11-01 US disclosed
EP-2426115-A2 Alkynyl derivatives as modulators of metabotropic glutamate receptors Addex Pharma SA (CH) 2012-03-07 EP disclosed
US-8101637-B2 Alkynyl derivatives as modulators of metatropic glutamate receptors ADDEX PHARMA SA (CH) 2012-01-24 US disclosed
WO-2011156478-A2 POLYMERS WITH TUNABLE BAND GAPS FOR PHOTONIC AND ELECTRONIC APPLICATIONS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2011-12-15 WO disclosed
WO-2011156478-A2 POLYMERS WITH TUNABLE BAND GAPS FOR PHOTONIC AND ELECTRONIC APPLICATIONS THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2011-12-15 WO disclosed
WO-2011103952-A1 ELECTRODE TREATMENT PROCESS FOR ORGANIC ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2011-09-01 WO disclosed
US-20090124625-A1 NOVEL ALKYNYL DERIVATIVES AS MODULATORS OF METATROPIC GLUTAMATE RECEPTORS ADDEX PHARMACEUTICALS SA (CH) 2009-05-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090124625-A1 NOVEL ALKYNYL DERIVATIVES AS MODULATORS OF METATROPIC GLUTAMATE RECEPTORS GRM5, GRM2, GRM1 KDM4E 1986/4885ALDH1A1 2496/4885CYP1A2 3019/4885
US-20130092912-A1 POLYMERS WITH TUNABLE BAND GAPS FOR PHOTONIC AND ELECTRONIC APPLICATIONS GJB2, PARG, PARN KDM4E 4406/4885ALDH1A1 1406/4885CYP1A2 2777/4885
US-20120277237-A1 NOVEL ALKYNYL DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS GRM5, GRM1, GRM2 KDM4E 1750/4885ALDH1A1 2153/4885CYP1A2 3599/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.