SCHEMBL1029640

SCHEMBL1029640

Cc1ccccc1C(=O)S

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.50
ERCC5 P28715 1/20 0.48
FEN1 P39748 1/20 0.48
HTT P42858 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.46
MYC P01106 1/20 0.45
KDM4E B2RXH2 1/20 0.45
ALDH1A1 P00352 1/20 0.45
HSD17B10 Q99714 1/20 0.45
POLB P06746 1/20 0.44
KMT2A Q03164 1/20 0.44
ELANE P08246 1/20 0.44
TYK2 P29597 1/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA3 P07451 1/20 0.44
CA4 P22748 1/20 0.44
CA6 P23280 1/20 0.44
CA5A P35218 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7340289 0.86 NPC1 (0.42) HPGDERCC5FEN1HTTSMN1; SMN2
SCHEMBL9539588 0.81 ESR1 (0.49) HPGDHTTMYCKDM4EALDH1A1
SCHEMBL1158059 0.81 CA12 (0.55) HPGDSMN1; SMN2KDM4EALDH1A1HSD17B10
SCHEMBL1596859 0.80 HPGD (0.50) HPGDERCC5FEN1HTTSMN1; SMN2
SCHEMBL709787 0.79 ALDH1A1 (0.67) HPGDHTTSMN1; SMN2MYCKDM4E
SCHEMBL29425530 0.79 HPGD (0.54) HPGDERCC5FEN1HTTSMN1; SMN2
SCHEMBL166603 0.79 HPGD (0.54) HPGDERCC5FEN1HTTSMN1; SMN2
SCHEMBL29387256 0.79 CYP3A4 (0.55) HPGDERCC5FEN1HTTSMN1; SMN2
SCHEMBL4270217 0.79 TSHR (0.47) HPGDERCC5FEN1HTTSMN1; SMN2
SCHEMBL333141 0.79 CYP3A4 (0.55) HPGDERCC5FEN1HTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240336740-A1 POLYTHIOL COMPOUNDS AND PROCESS FOR PREPARATION THEREOF HENKEL AG & CO KGAA (DE) 2024-10-10 US claimed
US-20240336575-A1 POLYTHIOL COMPOUNDS AND PROCESS FOR PREPARATION THEREOF HENKEL AG & CO KGAA (DE) 2024-10-10 US claimed
US-20240327341-A1 POLYTHIOL COMPOUNDS AND PROCESS FOR PREPARATION THEREOF HENKEL AG & CO KGAA (DE) 2024-10-03 US claimed
CN-118401566-A Polythiol compound and process for producing the same 汉高股份有限及两合公司 2024-07-26 CN claimed
CN-118401498-A Polythiol compound and process for producing the same 汉高股份有限及两合公司 2024-07-26 CN claimed
EP-4198062-B1 POLYTHIOL COMPOUNDS AND PROCESS FOR PREPARATION THEREOF HENKEL AG & CO KGAA (DE) 2024-07-17 EP claimed
EP-4198028-B1 POLYTHIOL COMPOUNDS AND PROCESS FOR PREPARATION THEREOF HENKEL AG & CO KGAA (DE) 2024-07-17 EP claimed
CN-114874413-B Dispersing resin for cathode electrophoretic coating matched with film pretreatment and preparation method and application thereof 上海金力泰化工股份有限公司 2024-03-01 CN claimed
CN-116660543-A Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof 中国人民解放军陆军军医大学第一附属医院 2023-08-29 CN claimed
WO-2023110271-A1 POLYTHIOL COMPOUNDS AND PROCESS FOR PREPARATION THEREOF HENKEL AG & CO. KGAA (DE) 2023-06-22 WO claimed
CN-107686468-B Method for recovering 1, 2-benzisothiazolin-3-ketone contained in solvent 连云港市三联化工有限公司 2020-06-19 CN claimed
EP-2699606-B1 POLYMERS FUNCTIONALIZED WITH A CARBOXYLIC OR THIOCARBOXYLIC ESTER CONTAINING A SILYLATED AMINO GROUP BRIDGESTONE CORP (JP) 2016-09-28 EP claimed
US-20160264909-A1 FRESHENING COMPOSITIONS RESISTING SCENT HABITUATION THE PROCTER & GAMBLE COMPANY 2016-09-15 US claimed
EP-2699606-A2 POLYMERS FUNCTIONALIZED WITH A CARBOXYLIC OR THIOCARBOXYLIC ESTER CONTAINING A SILYLATED AMINO GROUP Bridgestone Corporation (JP) 2014-02-26 EP claimed
US-20140018500-A1 Polymers Functionalized With A Carboxylic Or Thiocarboxylic Ester Containing A Silylated Amino Group BRIDGESTONE CORPORATION (JP) 2014-01-16 US claimed
WO-2012135451-A2 POLYMERS FUNCTIONALIZED WITH A CARBOXYLIC OR THIOCARBOXYLIC ESTER CONTAINING A SILYLATED AMINO GROUP BRIDGESTONE CORPORATION (JP) 2012-10-04 WO claimed
WO-2006091506-A2 NEUROPEPTIDE Y4 RECEPTOR AGONISTS BAYER PHARMACEUTICALS CORPORATION (US) 2006-08-31 WO claimed
EP-1349823-A1 PROCESS FOR BASE-PROMOTED CONDENSATION REACTIONS AND BASE REAGENT THEREFOR Crompton Corporation (US) 2003-10-08 EP claimed
WO-2002055466-A1 PROCESS FOR BASE-PROMOTED CONDENSATION REACTIONS AND BASE REAGENT THEREFOR CROMPTON CORPORATION (US) 2002-07-18 WO claimed
US-5466858-A Ruthenium catalyst, high selectivity with a carboxylic acid UBE INDUSTRIES, LTD. (JP) 1995-11-14 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240336575-A1 POLYTHIOL COMPOUNDS AND PROCESS FOR PREPARATION THEREOF VRK2, VRK1, PTMS HPGD 2478/4885ERCC5 3223/4885FEN1 1519/4885
US-20240327341-A1 POLYTHIOL COMPOUNDS AND PROCESS FOR PREPARATION THEREOF VCL, C9, VRK1 HPGD 841/4885ERCC5 756/4885FEN1 391/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.