SCHEMBL1158059

SCHEMBL1158059

O=C(S)c1ccccc1C(=O)S

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.55
CA1 P00915 2/20 0.55
CA2 P00918 2/20 0.55
CA4 P22748 2/20 0.55
CA6 P23280 2/20 0.55
CA7 P43166 2/20 0.55
CA9 Q16790 2/20 0.55
CA14 Q9ULX7 2/20 0.55
CA3 P07451 1/20 0.55
CA5A P35218 1/20 0.55
CA13 Q8N1Q1 1/20 0.55
CA5B Q9Y2D0 1/20 0.55
ALDH1A1 P00352 7/20 0.53
ALOX15 P16050 2/20 0.53
MAPT P10636 3/20 0.48
HDAC8 Q9BY41 1/20 0.48
KDM4E B2RXH2 3/20 0.43
HPGD P15428 3/20 0.43
CES2 O00748 2/20 0.43
CES1 P23141 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23509695 0.89 ALDH1A1 (0.74) CA12CA1CA2CA4CA6
SCHEMBL7280044 0.87 CA12 (0.44) CA12CA1CA2CA4CA6
SCHEMBL61047 0.83 KDM4E (0.61) CA12CA1CA2CA4CA6
SCHEMBL898951 0.83 MAPT (0.65) CA12CA1CA2CA4CA6
SCHEMBL8547386 0.83 AKR1C3 (0.68) CA12CA1CA2CA4CA6
SCHEMBL2927655 0.81 CES2 (0.65) CA12CA1CA2CA4CA6
SCHEMBL5573698 0.81 KDM4E (0.58) CA12CA1CA2CA4CA6
SCHEMBL10587193 0.81 NPC1 (0.47) CA12CA1CA2CA4CA6
SCHEMBL9522207 0.81 MAPT (0.62) CA12CA1CA2CA4CA6
SCHEMBL9335119 0.81 KDM4E (0.58) CA12CA1CA2CA4CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2292668-B2 Process for preparing polymers and compositions thereof LUBRIZOL CORP (US) 2025-09-10 EP disclosed
EP-2969201-B1 NON-PHTHALATE COMPOUNDS AS ELECTRON DONORS FOR POLYOLEFIN CATALYSTS FORMOSA PLASTICS CORP USA (US) 2022-05-04 EP disclosed
EP-2292668-B1 Process for preparing polymers and compositions thereof LUBRIZOL CORP (US) 2019-03-20 EP disclosed
US-20180037839-A1 Process for Preparing Polymers and Compositions Thereof LUBRIZOL CORP (US) 2018-02-08 US disclosed
US-9809780-B2 Process for preparing polymers and compositions thereof THE LUBRIZOL CORPORATION (US) 2017-11-07 US disclosed
US-9790291-B2 Non-phthalate compounds as electron donors for polyolefin catalysts FORMOSA PLASTICS CORPORATION, USA (US) 2017-10-17 US disclosed
CN-105452261-A Continuous process for the preparation of thiocarboxylate silane MOMENTIVE PERFORMANCE MAT INC 2016-03-30 CN disclosed
EP-2969201-A2 NON-PHTHALATE COMPOUNDS AS ELECTRON DONORS FOR POLYOLEFIN CATALYSTS Formosa Plastics Corporation, U.S.A. (US) 2016-01-20 EP disclosed
EP-1833852-B1 PROCESS FOR PREPARING LUBRICATING COMPOSITIONS LUBRIZOL CORP (US) 2015-05-27 EP disclosed
WO-2014160012-A2 NON-PHTHALATE COMPOUNDS AS ELECTRON DONORS FOR POLYOLEFIN CATALYSTS FORMOSA PLASTICS CORPORATION, USA (US) 2014-10-02 WO disclosed
US-7358310-B2 Compositions for use in golf balls ACUSHNET COMPANY (US) 2008-04-15 US disclosed
US-7358309-B2 core or the layer includes a composition formed from a base polymer, a crosslink initiator, and at least one additive; additive has at least one carbon-oxygen-boron linkage, carbon in the linkage being a secondary or tertiary carbon; enhances coefficient of restitution and/or reduces compression of core ACUSHNET COMPANY (US) 2008-04-15 US disclosed
US-7358308-B2 Compositions for use in golf balls ACUSHNET COMPANY (US) 2008-04-15 US disclosed
EP-1833852-A1 PROCESS FOR PREPARING POLYMERS AND COMPOSITIONS THEREOF THE LUBRIZOL CORPORATION (US) 2007-09-19 EP disclosed
US-20060281586-A1 Compositions for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2006-12-14 US disclosed
US-20060281587-A1 Compositions for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2006-12-14 US disclosed
WO-2006047393-A1 PROCESS FOR PREPARING POLYMERS AND COMPOSITIONS THEREOF THE LUBRIZOL CORPORATION (US) 2006-05-04 WO disclosed
US-20050245652-A1 Compositions for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-11-03 US disclosed
US-20050245657-A1 Compositions for use in golf balls JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-11-03 US disclosed
US-6224788-B1 AROMATIC UNSATURATED KETONE POLYMERS JSR CORPORATION (JP) 2001-05-01 US disclosed