Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.51 |
| ▸ | APLNR | P35414 | 4/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.48 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4303904 | 0.95 | OPRM1 (0.54) | MC4ROPRM1OPRK1APLNRCXCR4 | |
| SCHEMBL197800 | 0.94 | APLNR (0.49) | MC4ROPRM1OPRK1APLNRC5AR1 | |
| SCHEMBL4301705 | 0.89 | MC4R (0.52) | MC4ROPRM1OPRK1APLNRCXCR4 | |
| SCHEMBL4807584 | 0.88 | APLNR (0.56) | MC4ROPRM1OPRK1APLNRCXCR4 | |
| SCHEMBL4807604 | 0.88 | APLNR (0.56) | MC4ROPRM1OPRK1APLNRCXCR4 | |
| SCHEMBL4804787 | 0.86 | APLNR (0.55) | OPRM1OPRK1APLNRCXCR4 | |
| SCHEMBL4804770 | 0.86 | APLNR (0.55) | OPRM1OPRK1APLNRCXCR4 | |
| SCHEMBL1029282 | 0.85 | OPRM1 (0.52) | MC4ROPRM1OPRK1APLNRCXCR4 | |
| SCHEMBL1028505 | 0.84 | OPRM1 (0.56) | MC4ROPRM1OPRK1APLNRCXCR4 | |
| SCHEMBL1030624 | 0.84 | OPRM1 (0.55) | MC4ROPRM1OPRK1APLNRCXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2274328-A1 | PEPTIDES, PEPTIDOMIMETICS AND DERIVATIVES THEREOF, THE MANUFACTURING THEREOF AS WELL AS THEIR USE FOR PREPARING A THERAPEUTICALLY AND/OR PREVENTIVELY ACTIVE PHARMACEUTICAL COMPOSITION | Fibrex Medical Research & Development GmbH (AT) | 2011-01-19 | — | — | EP | disclosed |