SCHEMBL10298596

SCHEMBL10298596

COS(=O)(=O)c1cc(C)ccc1NC(C)=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.47
LMNA P02545 2/20 0.47
KMT2A Q03164 4/20 0.45
EPHX1 P07099 1/20 0.43
MEN1 O00255 1/20 0.42
ALDH1A1 P00352 1/20 0.42
TSHR P16473 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CA1 P00915 3/20 0.41
CA2 P00918 3/20 0.41
CA9 Q16790 3/20 0.41
PKM P14618 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
POLB P06746 2/20 0.40
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10298587 0.87 HPGD (0.44) HPGDLMNAKMT2AEPHX1MEN1
SCHEMBL10298593 0.83 HSD17B1 (0.51) LMNAKMT2AMEN1ALDH1A1TSHR
SCHEMBL16015147 0.82 KMT2A (0.48) HPGDLMNAKMT2AMEN1ALDH1A1
SCHEMBL27575211 0.81 CA1 (0.54) LMNAKMT2AALDH1A1TSHRSMN1; SMN2
SCHEMBL6363306 0.80 MEN1 (0.47) HPGDLMNAKMT2AMEN1ALDH1A1
SCHEMBL10298598 0.79 TSHR (0.50) HPGDLMNAALDH1A1TSHRSMN1; SMN2
SCHEMBL31294284 0.79 TSHR (0.50) HPGDLMNAALDH1A1TSHRSMN1; SMN2
SCHEMBL14389851 0.78 MEN1 (0.43) HPGDLMNAKMT2AMEN1ALDH1A1
SCHEMBL9001321 0.78 PKM (0.59) LMNAKMT2AMEN1ALDH1A1TSHR
SCHEMBL13433571 0.76 KMT2A (0.51) LMNAKMT2AMEN1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8828633-B2 Toner CANON KABUSHIKI KAISHA (JP) 2014-09-09 US disclosed
EP-2501733-B1 RESIN FOR TONERS, AND TONER CANON KK (JP) 2014-03-05 EP disclosed
US-20120172562-A1 RESIN FOR TONERS, AND TONER CANON KABUSHIKI KAISHA (JP) 2012-07-05 US disclosed