Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | CASP6 | P55212 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13973940 | 0.85 | KMT2A (0.50) | KMT2APOLBCASP6TDP1MAPT | |
| SCHEMBL27575211 | 0.85 | CA1 (0.54) | KMT2APOLBMAPTALDH1A1LMNA | |
| SCHEMBL7527649 | 0.84 | KMT2A (0.53) | KMT2APOLBCASP6TDP1MAPT | |
| SCHEMBL1813969 | 0.84 | TDP1 (0.43) | KMT2APOLBCASP6TDP1MAPT | |
| SCHEMBL9001321 | 0.82 | PKM (0.59) | KMT2APOLBTDP1MAPTMEN1 | |
| SCHEMBL10298596 | 0.82 | HPGD (0.47) | KMT2APOLBTDP1MAPTMEN1 | |
| SCHEMBL12960523 | 0.82 | L3MBTL1 (0.51) | KMT2APOLBCASP6TDP1MAPT | |
| SCHEMBL17491050 | 0.82 | GAA (0.61) | KMT2APOLBCASP6TDP1MAPT | |
| SCHEMBL3830815 | 0.81 | RAPGEF4 (0.59) | KMT2APOLBCASP6TDP1MAPT | |
| SCHEMBL9644847 | 0.81 | CASP6 (0.46) | KMT2APOLBCASP6TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2710431-B1 | TONER | CANON KK (JP) | 2017-09-13 | — | — | EP | disclosed |
| US-9029056-B2 | Toner | CANON KABUSHIKI KAISHA (JP) | 2015-05-12 | — | — | US | disclosed |
| US-8828633-B2 | Toner | CANON KABUSHIKI KAISHA (JP) | 2014-09-09 | — | — | US | disclosed |