Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6757780 | 0.83 | CA1 (0.46) | TRPA1TRPM8CA1CA2CA4 | |
| SCHEMBL6757777 | 0.83 | CA1 (0.46) | TRPA1TRPM8CA1CA2CA4 | |
| SCHEMBL15369688 | 0.83 | CA1 (0.46) | TRPA1TRPM8CA1CA2CA4 | |
| SCHEMBL6757779 | 0.83 | CA1 (0.46) | TRPA1TRPM8CA1CA2CA4 | |
| SCHEMBL6757782 | 0.83 | CA1 (0.46) | TRPA1TRPM8CA1CA2CA4 | |
| SCHEMBL15369721 | 0.83 | CA1 (0.46) | TRPA1TRPM8CA1CA2CA4 | |
| SCHEMBL7745825 | 0.82 | TRPA1 (0.39) | TRPA1TRPM8 | |
| SCHEMBL10297543 | 0.82 | TRPA1 (0.39) | TRPA1TRPM8 | |
| SCHEMBL7745828 | 0.82 | TRPA1 (0.39) | TRPA1TRPM8 | |
| SCHEMBL14879284 | 0.82 | CA1 (0.36) | TRPA1TRPM8CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3807241-B1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2022-04-13 | — | — | EP | disclosed |
| US-10988482-B2 | IRAK4 inhibitor and use thereof | Beijing Hanmi Pharmaceutical Co., Ltd. (CN) | 2021-04-27 | — | — | US | disclosed |
| EP-3807241-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | Givaudan SA (CH) | 2021-04-21 | — | — | EP | disclosed |
| US-20200062775-A1 | IRAK4 INHIBITOR AND USE THEREOF | Beijing Hanmi Pharmaceutical Co., Ltd. (CN) | 2020-02-27 | — | — | US | disclosed |
| WO-2019238568-A1 | IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2019-12-19 | — | — | WO | disclosed |
| US-9072676-B2 | Cyclohexyl carbamate compounds as skin and/or hair lightening actives | SYMRISE AG (DE) | 2015-07-07 | — | — | US | disclosed |
| US-9072676-B2 | Cyclohexyl carbamate compounds as skin and/or hair lightening actives | SYMRISE AG (DE) | 2015-07-07 | — | — | US | disclosed |
| US-9012497-B2 | Cyclohexyl carbamate compounds as active anti-cellulite ingredients | SYMRISE AG (DE) | 2015-04-21 | — | — | US | disclosed |
| US-9012497-B2 | Cyclohexyl carbamate compounds as active anti-cellulite ingredients | SYMRISE AG (DE) | 2015-04-21 | — | — | US | disclosed |
| US-8916511-B2 | Polysiloxanes having quaternary ammonium groups and use thereof | EVONIK DEGUSSA GMBH (DE) | 2014-12-23 | — | — | US | disclosed |
| US-20080305065-A1 | Novel polysiloxanes having quaternary ammonium groups, a process for the preparation thereof and the use thereof in cleaning and care formulations | GOLDSCHMIDT GMBH (DE) | 2008-12-11 | — | — | US | disclosed |
| WO-2008135208-A1 | FLUOROCARBON POLYMER-FREE PREPARATIONS BASED ON WATER AND/OR ORGANIC SOLVENTS AND THE USE THEREOF AS A FINISH ON FLEXIBLE SHEET MATERIAL | RUDOLF GMBH & CO. KG CHEMISCHE FABRIK (DE) | 2008-11-13 | — | — | WO | disclosed |
| US-20080274071-A1 | POWDERY STYLING AGENTS AND THE DISPENSER SYSTEMS THEREOF | HENKEL AG & CO. KGAA (DE) | 2008-11-06 | — | — | US | disclosed |
| US-20080261473-A1 | Polysiloxane and textile auxilary containing a polysiloxane | CHT R. BEITLICH GMBH (DE) | 2008-10-23 | — | — | US | disclosed |
| EP-1975193-A1 | Polysiloxane and textile aid containing a polysiloxane | CHT R. BEITLICH GmbH (DE) | 2008-10-01 | — | — | EP | disclosed |
| US-20080213208-A1 | Polyamino and/or Polyammonium/Polysiloxane Copolymer Compounds With Polyalkylene Oxide Units In Comb-Shaped Arrangement | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2008-09-04 | — | — | US | disclosed |
| US-20080194785-A1 | Composition Containing Polyamino-Polysiloxane And/Or Polyammonium-Polysiloxane Compounds On A Substrate | MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) | 2008-08-14 | — | — | US | disclosed |
| US-7390479-B2 | Branched polyorganosiloxane polymers | GE BAYER SILICONES GMBH & CO. KG (DE) | 2008-06-24 | — | — | US | disclosed |
| US-7329707-B2 | Partially quaternised, amino-functional organopolysiloxanes and their use in aqueous systems | RUDOLF GMBH & CO. KG CHEMISCHE FABRIK (DE) | 2008-02-12 | — | — | US | disclosed |
| US-20080027202-A1 | Novel polysiloxanes with quaternary ammonium groups, preparation thereof and use thereof as textile softeners | GOLDSCHMIDT GMBH (DE) | 2008-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10988482-B2 | IRAK4 inhibitor and use thereof | IRAK4, IRAK1, IRAK2 | TRPA1 3233/4885TRPM8 3770/4885CA1 4736/4885 |
| US-20080274071-A1 | POWDERY STYLING AGENTS AND THE DISPENSER SYSTEMS THEREOF | KRT18, PRKDC, PRKX | TRPA1 3659/4885TRPM8 3747/4885CA1 2373/4885 |
| US-20080305065-A1 | Novel polysiloxanes having quaternary ammonium groups, a process for the preparation thereof and the use thereof in cleaning and care formulations | SIN3A, POLD3, SUMO3 | TRPA1 2721/4885TRPM8 3654/4885CA1 3117/4885 |
| US-20080213208-A1 | Polyamino and/or Polyammonium/Polysiloxane Copolymer Compounds With Polyalkylene Oxide Units In Comb-Shaped Arrangement | PARN, PARG, PUF60 | TRPA1 687/4885TRPM8 2348/4885CA1 1370/4885 |
| US-20200062775-A1 | IRAK4 INHIBITOR AND USE THEREOF | IRAK4, IRAK1, IRAK2 | TRPA1 3233/4885TRPM8 3770/4885CA1 4736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.