Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29353358 | 0.85 | RAB9A (0.55) | LMNAACHEPKMGAAMEN1 | |
| SCHEMBL11773130 | 0.81 | ACHE (0.51) | LMNAKDM4ECYP3A4HTR1DACHE | |
| SCHEMBL10175247 | 0.80 | AOC3 (0.44) | — | |
| SCHEMBL13233739 | 0.77 | KDM4E (0.46) | KDM4ECYP3A4CA12CA9GAA | |
| SCHEMBL10480044 | 0.74 | KDM4E (0.67) | LMNAKDM4ECYP3A4ACHEMAPT | |
| SCHEMBL5861768 | 0.74 | LMNA (0.49) | LMNAKDM4ECYP3A4ACHEMAPT | |
| SCHEMBL12861332 | 0.73 | HSD17B10 (0.47) | LMNAKDM4ECYP3A4MAPTTP53 | |
| SCHEMBL3049927 | 0.73 | LMNA (0.48) | LMNAKDM4ECYP3A4ACHEMAPT | |
| SCHEMBL10591054 | 0.73 | CYP3A4 (0.56) | LMNAKDM4ECYP3A4ACHEMAPT | |
| SCHEMBL792335 | 0.72 | FSCN1 (0.41) | LMNAMAPTPOLBGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1550662-B1 | ADENINE COMPOUND AND USE THEREOF | DAINIPPON SUMITOMO PHARMA CO (JP) | 2012-07-04 | — | — | EP | disclosed |