Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 5/20 | 0.55 |
| ▸ | MMP2 | P08253 | 5/20 | 0.55 |
| ▸ | MMP9 | P14780 | 5/20 | 0.55 |
| ▸ | EGFR | P00533 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | STAT1 | P42224 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10008854 | 1.00 | MMP1 (0.55) | MMP1MMP2MMP9EGFRNPC1 | |
| SCHEMBL10008857 | 1.00 | MMP1 (0.55) | MMP1MMP2MMP9EGFRNPC1 | |
| SCHEMBL10299116 | 0.89 | MMP1 (0.55) | MMP1MMP2MMP9EGFRNPC1 | |
| SCHEMBL10009481 | 0.77 | MMP1 (0.57) | MMP1MMP2MMP9EGFRNPC1 | |
| SCHEMBL10009478 | 0.77 | MMP1 (0.57) | MMP1MMP2MMP9EGFRNPC1 | |
| SCHEMBL10008771 | 0.76 | RAB9A (0.49) | RAB9ALTB4RMAPTSMN1; SMN2KMT2A | |
| SCHEMBL10008580 | 0.74 | KMT2A (0.61) | MMP1MMP2MMP9EGFRNPC1 | |
| SCHEMBL10008577 | 0.74 | KMT2A (0.61) | MMP1MMP2MMP9EGFRNPC1 | |
| SCHEMBL10010523 | 0.74 | EGFR (0.62) | MMP1MMP2MMP9EGFRNPC1 | |
| SCHEMBL10299114 | 0.74 | EGFR (0.62) | MMP1MMP2MMP9EGFRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8883793-B2 | Tubulin inhibitors and methods of using the same | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) | 2014-11-11 | — | — | US | disclosed |
| US-20120172374-A1 | NOVEL TUBULIN INHIBITORS AND METHODS OF USING THE SAME | DEVELOPMENT CENTER FOR BIOTECHNOLOGY (TW) | 2012-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120172374-A1 | NOVEL TUBULIN INHIBITORS AND METHODS OF USING THE SAME | TUBB1, TUBA1C, TUBB | MMP1 2605/4885MMP2 3553/4885MMP9 4303/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.