Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 10/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7709836 | 0.95 | SMN1; SMN2 (0.47) | SMN1; SMN2HTR1AADRA1BADRA1ADRD2 | |
| SCHEMBL14820495 | 0.93 | SMN1; SMN2 (0.46) | SMN1; SMN2HTR1AADRA1BADRA1ADRD2 | |
| SCHEMBL12601432 | 0.90 | SMN1; SMN2 (0.37) | SMN1; SMN2HTR1AADRA1BADRA1ACYP11B2 | |
| SCHEMBL14806816 | 0.81 | SMN1; SMN2 (0.41) | SMN1; SMN2HTR1AADRA1BADRA1ADRD2 | |
| SCHEMBL13339631 | 0.79 | TSHR (0.33) | SMN1; SMN2 | |
| SCHEMBL14806790 | 0.79 | SMN1; SMN2 (0.40) | SMN1; SMN2HTR1AADRA1BADRA1ADRD2 | |
| SCHEMBL10299246 | 0.75 | HTR1A (0.40) | SMN1; SMN2HTR1AADRA1BADRA1ADRD2 | |
| SCHEMBL12600977 | 0.72 | HTR1A (0.48) | HTR1AADRA1BADRA1ADRD2ADRA1D | |
| SCHEMBL761687 | 0.70 | MEN1 (0.39) | HTR1ADRD2 | |
| SCHEMBL24987395 | 0.70 | SMN1; SMN2 (0.33) | SMN1; SMN2HTR1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9221765-B2 | Inhibition and dispersion of bacterial biofilms with benzimidazole derivatives | NORTH CAROLINA STATE UNIVERSITY (US) | 2015-12-29 | — | — | US | disclosed |
| US-20120171129-A1 | Inhibition and Dispersion of Bacterial Biofilms with Benzimidazole Derivatives | NORTH CAROLINA STATE UNIVERSITY | 2012-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120171129-A1 | Inhibition and Dispersion of Bacterial Biofilms with Benzimidazole Derivatives | SBDS, DBI, BRI3BP | SMN1; SMN2 4867/4885HTR1A 4159/4885ADRA1B 3713/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.