Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 11/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14820495 | 0.98 | SMN1; SMN2 (0.46) | SMN1; SMN2HTR1AADRA1BADRA1ADRD2 | |
| SCHEMBL10299522 | 0.95 | SMN1; SMN2 (0.43) | SMN1; SMN2HTR1AADRA1BADRA1ADRD2 | |
| SCHEMBL12601432 | 0.90 | SMN1; SMN2 (0.37) | SMN1; SMN2HTR1AADRA1BADRA1A | |
| SCHEMBL14806816 | 0.85 | SMN1; SMN2 (0.41) | SMN1; SMN2HTR1AADRA1BADRA1ADRD2 | |
| SCHEMBL14806790 | 0.83 | SMN1; SMN2 (0.40) | SMN1; SMN2HTR1AADRA1BADRA1ADRD2 | |
| SCHEMBL13339631 | 0.79 | TSHR (0.33) | SMN1; SMN2 | |
| SCHEMBL12600977 | 0.76 | HTR1A (0.48) | HTR1AADRA1BADRA1ADRD2ADRA1D | |
| SCHEMBL9271889 | 0.75 | SMN1; SMN2 (0.43) | SMN1; SMN2HTR1AADRA1BADRA1ADRD2 | |
| SCHEMBL7301175 | 0.75 | SMN1; SMN2 (0.43) | SMN1; SMN2HTR1AADRA1BADRA1ADRD2 | |
| SCHEMBL12601433 | 0.75 | CHRM2 (0.46) | SMN1; SMN2HTR1AADRA1BADRA1ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11780946-B2 | Alternating copolymer, method of producing alternating copolymer, method of producing polymeric compound, and method of forming resist pattern | TOKYO OHKA KOGYO CO., LTD. (JP) | 2023-10-10 | — | — | US | disclosed |
| US-11780946-B2 | Alternating copolymer, method of producing alternating copolymer, method of producing polymeric compound, and method of forming resist pattern | TOKYO OHKA KOGYO CO., LTD. (JP) | 2023-10-10 | — | — | US | disclosed |
| US-11084829-B2 | Ubiquitin-specific-processing protease 7 (USP7) modulators and uses thereof | RAPT THERAPEUTICS, INC. (US) | 2021-08-10 | — | — | US | disclosed |
| US-20210230332-A1 | ALTERNATING COPOLYMER, METHOD OF PRODUCING ALTERNATING COPOLYMER, METHOD OF PRODUCING POLYMERIC COMPOUND, AND METHOD OF FORMING RESIST PATTERN | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-07-29 | — | — | US | disclosed |
| US-10722514-B2 | Ubiquitin-specific-processing protease 7 (USP7) modulators and uses thereof | RAPT THERAPEUTICS, INC. (US) | 2020-07-28 | — | — | US | disclosed |
| WO-2020068600-A1 | UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF | RAPT THERAPEUTICS, INC. (US) | 2020-04-02 | — | — | WO | disclosed |
| US-20200095260-A1 | UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF | RAPT THERAPEUTICS, INC. | 2020-03-26 | — | — | US | disclosed |
| US-20190142834-A1 | UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF | RAPT THERAPEUTICS, INC. | 2019-05-16 | — | — | US | disclosed |
| EP-2978820-B1 | WAVELENGTH CONVERSION FILMS WITH MULTIPLE PHOTOSTABLE ORGANIC CHROMOPHORES | NITTO DENKO CORP (JP) | 2018-03-21 | — | — | EP | disclosed |
| EP-2788450-B1 | WAVELENGTH CONVERSION MATERIAL AS ENCAPSULANT FOR SOLAR MODULE SYSTEMS TO ENHANCE SOLAR HARVESTING EFFICIENCY | NITTO DENKO CORP (JP) | 2017-06-21 | — | — | EP | disclosed |
| US-7759388-B2 | Phenylalanine derivatives | AJINOMOTO CO., INC. (JP) | 2010-07-20 | — | — | US | disclosed |
| US-7592419-B2 | Macrocyclic inhibitors of hepatitis C virus NS3-serine protease | SCHERING CORPORATION (US) | 2009-09-22 | — | — | US | disclosed |
| US-20090131491-A1 | ISOXAZOLE DERIVATIVE AND ISOTHIAZOLE DERIVATIVE HAVING INHIBITORY ACTIVITY ON 11(beta)-HYDROXYSTEROID DEHYDROGENASE TYPE I | SHIONOGI & CO., LTD. (JP) | 2009-05-21 | — | — | US | disclosed |
| US-20090069320-A1 | Substituted 4-Amino-Quinazoline Compounds with Metabotropic Glutamate Receptor Regulating Activity and Uses Thereof | GRUENENTHAL GMBH (DE) | 2009-03-12 | — | — | US | disclosed |
| US-20090048236-A1 | NEW PHENYLALANINE DERIVATIVES | AJINOMOTO CO. INC (JP) | 2009-02-19 | — | — | US | disclosed |
| US-20090048236-A1 | NEW PHENYLALANINE DERIVATIVES | AJINOMOTO CO. INC (JP) | 2009-02-19 | — | — | US | disclosed |
| US-7452905-B2 | Phenylalanine derivatives | AJINOMOTO CO., INC. (JP) | 2008-11-18 | — | — | US | disclosed |
| US-7452905-B2 | Phenylalanine derivatives | AJINOMOTO CO., INC. (JP) | 2008-11-18 | — | — | US | disclosed |
| US-6566361-B2 | Concurrent administration of acetaminophen with an azapirone such as buspirone. | LABORATORIES, UPSA (FR) | 2003-05-20 | — | — | US | disclosed |
| US-6566361-B2 | Concurrent administration of acetaminophen with an azapirone such as buspirone. | LABORATORIES, UPSA (FR) | 2003-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090048236-A1 | NEW PHENYLALANINE DERIVATIVES | ITGB4, VCAM1, ITGA4 | SMN1; SMN2 3291/4885HTR1A 1571/4885ADRA1B 328/4885 |
| US-20190142834-A1 | UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF | USP7, SENP7, USP8 | SMN1; SMN2 3154/4885HTR1A 4032/4885ADRA1B 4450/4885 |
| US-20200095260-A1 | UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 7 (USP7) MODULATORS AND USES THEREOF | USP7, SENP7, USP8 | SMN1; SMN2 3154/4885HTR1A 4032/4885ADRA1B 4450/4885 |
| US-20090131491-A1 | ISOXAZOLE DERIVATIVE AND ISOTHIAZOLE DERIVATIVE HAVING INHIBITORY ACTIVITY ON 11(beta)-HYDROXYSTEROID DEHYDROGENASE TYPE I | HSD3B1, NR5A1, HSD11B1 | SMN1; SMN2 4090/4885HTR1A 1409/4885ADRA1B 172/4885 |
| US-10722514-B2 | Ubiquitin-specific-processing protease 7 (USP7) modulators and uses thereof | USP7, SENP7, USP8 | SMN1; SMN2 3154/4885HTR1A 4032/4885ADRA1B 4450/4885 |
| US-11084829-B2 | Ubiquitin-specific-processing protease 7 (USP7) modulators and uses thereof | USP7, SENP7, USP8 | SMN1; SMN2 3154/4885HTR1A 4032/4885ADRA1B 4450/4885 |
| US-20090069320-A1 | Substituted 4-Amino-Quinazoline Compounds with Metabotropic Glutamate Receptor Regulating Activity and Uses Thereof | GRM1, GRIN1, GRM2 | SMN1; SMN2 1854/4885HTR1A 287/4885ADRA1B 737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.