Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 7/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.40 |
| ▸ | CASP2 | P42575 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17297122 | 1.00 | PAOX (0.48) | PAOXADRA1AKDM4EMAPK1HIF1A | |
| SCHEMBL9137891 | 0.98 | PAOX (0.46) | PAOXADRA1AKDM4EMAPK1HIF1A | |
| SCHEMBL18769692 | 0.92 | KDM4E (0.39) | PAOXADRA1AKDM4EMAPK1HIF1A | |
| SCHEMBL8775297 | 0.89 | KDM4E (0.56) | PAOXADRA1AKDM4EMAPK1HIF1A | |
| SCHEMBL8775294 | 0.89 | KDM4E (0.56) | PAOXADRA1AKDM4EMAPK1HIF1A | |
| SCHEMBL8775499 | 0.89 | KDM4E (0.56) | PAOXADRA1AKDM4EMAPK1HIF1A | |
| SCHEMBL8775285 | 0.89 | KDM4E (0.56) | PAOXADRA1AKDM4EMAPK1HIF1A | |
| SCHEMBL59429 | 0.89 | KDM4E (0.56) | PAOXADRA1AKDM4EMAPK1HIF1A | |
| SCHEMBL8774992 | 0.89 | KDM4E (0.56) | PAOXADRA1AKDM4EMAPK1HIF1A | |
| SCHEMBL907569 | 0.87 | KDM4E (0.52) | PAOXADRA1AKDM4EMAPK1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8217173-B2 | Fluoride-releasing compositions | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) | 2012-07-10 | — | — | US | disclosed |
| US-20100261902-A1 | Fluoride-Releasing Compositions | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY (US) | 2010-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261902-A1 | Fluoride-Releasing Compositions | CHERP, ORAI1, CAD | PAOX 3972/4885ADRA1A 4031/4885KDM4E 3444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.