Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.37 |
| ▸ | ACACB | O00763 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ACACA | Q13085 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10303365 | 0.91 | MAOA (0.35) | MAOAMAOBGPR119MEN1KMT2A | |
| SCHEMBL10303251 | 0.89 | MAOA (0.35) | MAOAMAOBGPR119ACACBNAAA | |
| SCHEMBL10303354 | 0.89 | MAOA (0.34) | MAOAMAOBGPR119ACACBACACA | |
| SCHEMBL13586399 | 0.88 | GPR119 (0.38) | MAOAMAOBGPR119ACACBFFAR1 | |
| SCHEMBL10302634 | 0.87 | GPR119 (0.36) | MAOAMAOBGPR119FFAR1NAAA | |
| SCHEMBL10302631 | 0.87 | GPR119 (0.37) | MAOAMAOBGPR119ACACBFFAR1 | |
| SCHEMBL12907931 | 0.87 | MAOA (0.36) | MAOAMAOBGPR119ACACBMEN1 | |
| SCHEMBL14766390 | 0.86 | HTR1A (0.34) | MAOAMAOBGPR119NAAAKCNH2 | |
| SCHEMBL11940000 | 0.86 | MAOA (0.39) | MAOAMAOBFFAR1SCN3AKCNH2 | |
| SCHEMBL10302641 | 0.85 | HTR1A (0.34) | MAOAMAOBGPR119FFAR1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8216489-B2 | Three-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-07-10 | — | — | US | disclosed |
| WO-2009125668-A1 | TRICYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | チッソ株式会社 (JP) | 2009-10-15 | — | — | WO | disclosed |