Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 4/20 | 0.51 |
| ▸ | HRH1 | P35367 | 4/20 | 0.51 |
| ▸ | ACE | P12821 | 3/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10305158 | 0.84 | HRH2 (0.46) | HRH2HRH1HPGDFPR2 | |
| SCHEMBL10725320 | 0.82 | FAAH (0.67) | ACEACE2MC4RFAAHPSMB5 | |
| SCHEMBL10725327 | 0.82 | FAAH (0.67) | ACEACE2MC4RFAAHPSMB5 | |
| SCHEMBL4205338 | 0.80 | FPR2 (0.52) | FPR2 | |
| SCHEMBL4214360 | 0.80 | FPR2 (0.52) | FPR2 | |
| SCHEMBL5552607 | 0.80 | FPR2 (0.52) | FPR2 | |
| SCHEMBL1644393 | 0.80 | MC4R (0.58) | MC4RPSMB5FPR2 | |
| Hydrochloric Acid SCHEMBL4725522 | 0.79 | FPR2 (0.51) | FPR2 | |
| SCHEMBL1644278 | 0.79 | MC4R (0.59) | HPGDMC4RPSMB5FPR2 | |
| SCHEMBL14311686 | 0.79 | UGCG (0.51) | HPGDMC4RFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2474534-A1 | 3-Aryl-3-hydroxy-2-amino-propionic acid amides, 3-heteroaryl-3-hydroxy-2-amino-propionic acid amides and related compounds having analgesic and/or immunostimulant activity | Allergan, Inc. (US) | 2012-07-11 | — | — | EP | disclosed |