Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 7/20 | 0.52 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | FPR1 | P21462 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4205338 | 1.00 | FPR2 (0.52) | FPR2MMP1MMP3CHRM1KMT2A | |
| SCHEMBL4214360 | 1.00 | FPR2 (0.52) | FPR2MMP1MMP3CHRM1KMT2A | |
| Hydrochloric Acid SCHEMBL4725522 | 0.99 | FPR2 (0.51) | FPR2MMP1MMP3CHRM1KMT2A | |
| SCHEMBL6252653 | 0.88 | MMP1 (0.51) | FPR2MMP1MMP3CHRM1KMT2A | |
| SCHEMBL13375723 | 0.82 | CHRM1 (0.44) | FPR2MMP1MMP3CHRM1KMT2A | |
| SCHEMBL16289260 | 0.82 | FPR2 (0.53) | FPR2MMP1MMP3KMT2AMEN1 | |
| SCHEMBL16289262 | 0.82 | FPR2 (0.53) | FPR2MMP1MMP3KMT2AMEN1 | |
| SCHEMBL10305175 | 0.82 | CHRM1 (0.44) | FPR2MMP1MMP3CHRM1KMT2A | |
| SCHEMBL14305072 | 0.82 | TGM2 (0.54) | FPR2 | |
| SCHEMBL13375717 | 0.81 | HRH2 (0.58) | KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1841743-A1 | 3-ARYL-3-HYDROXY-2-AMINO-PROPIONIC ACID AMIDES, 3-HETEROARYL-3-HYDROXY-2-AMINO-PROPIONIC ACID AMIDES AND RELATED COMPOUNDS HAVING ANALGESIC AND/OR IMMUNO STIMULANT ACTIVITY | Allergan, Inc. (US) | 2007-10-10 | — | — | EP | disclosed |
| WO-2006081273-A1 | 3-ARYL-3-HYDROXY-2-AMINO-PROPIONIC ACID AMIDES, 3-HETEROAYRYL-3-HYDROXY-2-AMINO-PROPIONIC ACID AMIDES AND RELATED COMPOUNDS HAVING ANALGESIC AND/OR IMMUNOSTIMULANT ACTIVITY | ALLERGAN, INC. (US) | 2006-08-03 | — | — | WO | disclosed |