Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1032660 | 0.81 | CYP1A2 (0.37) | HSP90AA1HSP90AB1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1027914 | 0.78 | CYP2D6 (0.40) | HSP90AA1HSP90AB1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL16247253 | 0.71 | CRHR1 (0.42) | HSP90AA1HSP90AB1ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL756089 | 0.71 | MAPT (0.38) | MAPTSMN1; SMN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL1029805 | 0.69 | ALDH1A1 (0.57) | HSP90AA1HSP90AB1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL1028790 | 0.69 | ALDH1A1 (0.47) | MAPTSMN1; SMN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL28203965 | 0.69 | MAPT (0.41) | MAPTSMN1; SMN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL13690118 | 0.67 | CA2 (0.42) | MAPTSMN1; SMN2ALDH1A1KDM4EMEN1 | |
| SCHEMBL13556609 | 0.67 | CA1 (0.42) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL28234441 | 0.67 | ALDH1A1 (0.42) | MAPTSMN1; SMN2ALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1474377-B1 | NITROSOPHENOLS AND C-NITROSOANILINES AS POLYMERIZATION INHIBITORS | CHEMTURA CORP (US) | 2011-01-19 | — | — | EP | claimed |
| US-7125475-B2 | Nitrosophenols and C-nitrosoanilines as polymerization inhibitors | CROMPTON CORPORATION (US) | 2006-10-24 | — | — | US | claimed |
| EP-1474377-A1 | NITROSOPHENOLS AND C-NITROSOANILINES AS POLYMERIZATION INHIBITORS | Crompton Corporation (US) | 2004-11-10 | — | — | EP | claimed |
| WO-2003070687-A1 | NITROSOPHENOLS AND C-NITROSOANILINES AS POLYMERIZATION INHIBITORS | CROMPTON CORPORATION (US) | 2003-08-28 | — | — | WO | claimed |
| US-20030155227-A1 | Nitrosophenols and C-nitrosoanilines as polymerization inhibitors | CROMPTON CORPORATION | 2003-08-21 | — | — | US | claimed |
| US-20180361319-A1 | METHOD FOR IMPROVED REACTVE MONOMER PRODUCTION WITH MEMBRANE FILTRATION | EVONIK DEGUSSA GMBH (DE) | 2018-12-20 | — | — | US | disclosed |
| EP-3197596-B1 | METHOD FOR IMPROVED REACTIVE MONOMER PRODUCTION WITH MEMBRANE FILTRATION | EVONIK DEGUSSA GMBH (DE) | 2018-11-07 | — | — | EP | disclosed |
| EP-2993164-B1 | Phenolic (thio) acetals as inhibitors of the polymerisation of olefinically unsaturated monomers | EVONIK DEGUSSA GMBH (DE) | 2017-02-15 | — | — | EP | disclosed |
| EP-2993164-A1 | Phenolic (thio) acetals as inhibitors of the polymerisation of olefinically unsaturated monomers | Evonik Degussa GmbH (DE) | 2016-03-09 | — | — | EP | disclosed |
| EP-1474377-B1 | NITROSOPHENOLS AND C-NITROSOANILINES AS POLYMERIZATION INHIBITORS | CHEMTURA CORP (US) | 2011-01-19 | — | — | EP | disclosed |
| US-7125475-B2 | Nitrosophenols and C-nitrosoanilines as polymerization inhibitors | CROMPTON CORPORATION (US) | 2006-10-24 | — | — | US | disclosed |
| EP-1474377-A1 | NITROSOPHENOLS AND C-NITROSOANILINES AS POLYMERIZATION INHIBITORS | Crompton Corporation (US) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003070687-A1 | NITROSOPHENOLS AND C-NITROSOANILINES AS POLYMERIZATION INHIBITORS | CROMPTON CORPORATION (US) | 2003-08-28 | — | — | WO | disclosed |
| US-20030155227-A1 | Nitrosophenols and C-nitrosoanilines as polymerization inhibitors | CROMPTON CORPORATION | 2003-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180361319-A1 | METHOD FOR IMPROVED REACTVE MONOMER PRODUCTION WITH MEMBRANE FILTRATION | PUF60, MAX, SAMM50 | HSP90AA1 4497/4885HSP90AB1 4405/4885MAPT 1780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.