Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.43 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1810781 | 0.84 | LTA4H (0.55) | PRSS1PRSS2PRSS3KMT2AALDH1A1 | |
| SCHEMBL8064264 | 0.84 | LTA4H (0.55) | PRSS1PRSS2PRSS3KMT2AALDH1A1 | |
| SCHEMBL1810782 | 0.83 | PRSS1 (0.47) | ELANEPRSS1PRSS2PRSS3KMT2A | |
| SCHEMBL27842369 | 0.82 | LTA4H (0.52) | PRSS1PRSS2PRSS3KMT2AALDH1A1 | |
| SCHEMBL19491916 | 0.81 | LTA4H (0.46) | PRSS1PRSS2PRSS3KMT2AALDH1A1 | |
| SCHEMBL28497163 | 0.80 | PRSS1 (0.44) | ELANEPRSS1PRSS2PRSS3KMT2A | |
| SCHEMBL21319413 | 0.79 | SLC15A1 (0.50) | KMT2AALDH1A1LMNALTA4HMEN1 | |
| SCHEMBL4280827 | 0.78 | SMN1; SMN2 (0.44) | ALDH1A1MAPTLTA4HSMN1; SMN2 | |
| SCHEMBL666850 | 0.77 | ALDH1A1 (0.48) | ELANEPRSS1PRSS2PRSS3KMT2A | |
| SCHEMBL31614987 | 0.77 | ATM (0.40) | ELANEPRSS1PRSS2PRSS3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2474306-A1 | PARTICLE COMPOSITION AND MEDICINAL COMPOSITION COMPRISING SAME | NanoCarrier Co., Ltd. (JP) | 2012-07-11 | — | — | EP | disclosed |