SCHEMBL10307018

SCHEMBL10307018

CC1(C)c2cc(-c3ccc4oc5ccccc5c4c3)ccc2-c2ccc(N(c3ccc(-c4cccc5c4oc4ccccc45)cc3)c3ccc(-c4cccc5c4oc4ccccc45)cc3)cc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.43
PRKDC P78527 3/20 0.36
HSP90AA1 P07900 1/20 0.34
HSP90AB1 P08238 1/20 0.34
GGPS1 O95749 1/20 0.34
PTPRF P10586 1/20 0.33
PTPN2 P17706 1/20 0.33
PTPN1 P18031 1/20 0.33
ALK Q9UM73 4/20 0.32
PTGES2 Q9H7Z7 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
KDM4E B2RXH2 1/20 0.32
NPC1 O15118 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
RAB9A P51151 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10307022 1.00 ALOX5 (0.43) ALOX5PRKDCHSP90AA1HSP90AB1GGPS1
SCHEMBL9916928 0.98 ALOX5 (0.41) ALOX5PRKDCHSP90AA1HSP90AB1GGPS1
SCHEMBL10307122 0.97 ALOX5 (0.41) ALOX5PRKDCHSP90AA1HSP90AB1GGPS1
SCHEMBL21375283 0.97 ALOX5 (0.41) ALOX5PRKDCHSP90AA1HSP90AB1GGPS1
SCHEMBL10307118 0.97 ALOX5 (0.41) ALOX5PRKDCHSP90AA1HSP90AB1GGPS1
SCHEMBL10307126 0.97 ALOX5 (0.41) ALOX5PRKDCHSP90AA1HSP90AB1GGPS1
SCHEMBL10307121 0.97 ALOX5 (0.41) ALOX5PRKDCHSP90AA1HSP90AB1GGPS1
SCHEMBL10307024 0.97 ALOX5 (0.45) ALOX5PRKDCHSP90AA1HSP90AB1GGPS1
SCHEMBL10307015 0.97 ALOX5 (0.45) ALOX5PRKDCHSP90AA1HSP90AB1GGPS1
SCHEMBL12136257 0.96 ALOX5 (0.40) ALOX5PRKDCHSP90AA1HSP90AB1GGPS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9972786-B2 Aromatic amine derivative, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-05-15 US disclosed
US-9972786-B2 Aromatic amine derivative, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-05-15 US disclosed
US-20150255729-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2015-09-10 US disclosed
US-20150255729-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2015-09-10 US disclosed
US-9054322-B2 Aromatic amine derivative, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2015-06-09 US disclosed
US-9054322-B2 Aromatic amine derivative, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2015-06-09 US disclosed
US-9024521-B2 Organic EL display device and method of manufacturing the same SONY CORPORATION (JP) 2015-05-05 US disclosed
US-9024521-B2 Organic EL display device and method of manufacturing the same SONY CORPORATION (JP) 2015-05-05 US disclosed
US-8823255-B2 Organic el display device and method of manufacturing the same SONY CORPORATION (JP) 2014-09-02 US disclosed
US-8823255-B2 Organic el display device and method of manufacturing the same SONY CORPORATION (JP) 2014-09-02 US disclosed
US-20120242218-A1 ORGANIC ELECTROLUMINESCENCE DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF SONY CORPORATION (JP) 2012-09-27 US disclosed
US-20120242218-A1 ORGANIC ELECTROLUMINESCENCE DISPLAY DEVICE AND MANUFACTURING METHOD THEREOF SONY CORPORATION (JP) 2012-09-27 US disclosed
US-20120175600-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-07-12 US disclosed
US-20120175600-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-07-12 US disclosed
US-20110278551-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2011-11-17 US disclosed
US-20110278551-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2011-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120175600-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT TYR, SLC7A5, SLC18A1 ALOX5 1326/4885PRKDC 2435/4885HSP90AA1 4361/4885
US-20150255729-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT SLC7A5, ALKBH3, TYR ALOX5 1384/4885PRKDC 2084/4885HSP90AA1 4464/4885
US-20110278551-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT SLC7A5, ALKBH3, TYR ALOX5 1384/4885PRKDC 2084/4885HSP90AA1 4464/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.