SCHEMBL10307121

SCHEMBL10307121

CC1(C)c2cc(-c3ccccc3)ccc2-c2ccc(N(c3ccc(-c4ccc(-c5ccc6oc7ccccc7c6c5)cc4)cc3)c3ccc(-c4cccc5c4oc4ccccc45)cc3)cc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.41
GGPS1 O95749 1/20 0.34
PRKDC P78527 3/20 0.34
PLA2G2A P14555 3/20 0.34
PLA2G4A P47712 3/20 0.34
PTPRF P10586 1/20 0.34
PTPN2 P17706 1/20 0.34
PTPN1 P18031 1/20 0.34
HSP90AA1 P07900 1/20 0.33
HSP90AB1 P08238 1/20 0.33
PLA2G10 O15496 1/20 0.33
PTGES2 Q9H7Z7 1/20 0.32
PIM1 P11309 1/20 0.32
CSNK2A2 P19784 1/20 0.32
CSNK2B P67870 1/20 0.32
PIM3 Q86V86 1/20 0.32
PIM2 Q9P1W9 1/20 0.32
CDC14B O60729 1/20 0.31
CDC14A Q9UNH5 1/20 0.31
ALK Q9UM73 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10307126 1.00 ALOX5 (0.41) ALOX5GGPS1PRKDCPLA2G2APLA2G4A
SCHEMBL10307122 1.00 ALOX5 (0.41) ALOX5GGPS1PRKDCPLA2G2APLA2G4A
SCHEMBL10307118 1.00 ALOX5 (0.41) ALOX5GGPS1PRKDCPLA2G2APLA2G4A
SCHEMBL10307043 0.99 ALOX5 (0.41) ALOX5GGPS1PRKDCPLA2G2APLA2G4A
SCHEMBL10307117 0.98 ALOX5 (0.41) ALOX5GGPS1PRKDCPLA2G2APLA2G4A
SCHEMBL10307125 0.98 ALOX5 (0.43) ALOX5GGPS1PRKDCPLA2G2APLA2G4A
SCHEMBL10307040 0.97 ALOX5 (0.41) ALOX5GGPS1PRKDCPLA2G2APLA2G4A
SCHEMBL10307022 0.97 ALOX5 (0.43) ALOX5GGPS1PRKDCPLA2G2APLA2G4A
SCHEMBL10307018 0.97 ALOX5 (0.43) ALOX5GGPS1PRKDCPLA2G2APLA2G4A
SCHEMBL21375283 0.96 ALOX5 (0.41) ALOX5GGPS1PRKDCPTPRFPTPN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9972786-B2 Aromatic amine derivative, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-05-15 US disclosed
US-9972786-B2 Aromatic amine derivative, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2018-05-15 US disclosed
US-20150255729-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2015-09-10 US disclosed
US-20150255729-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2015-09-10 US disclosed
US-9054322-B2 Aromatic amine derivative, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2015-06-09 US disclosed
US-9054322-B2 Aromatic amine derivative, and organic electroluminescent element IDEMITSU KOSAN CO., LTD. (JP) 2015-06-09 US disclosed
US-20120175600-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-07-12 US disclosed
US-20120175600-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2012-07-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120175600-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT TYR, SLC7A5, SLC18A1 ALOX5 1326/4885GGPS1 4077/4885PRKDC 2435/4885
US-20150255729-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT SLC7A5, ALKBH3, TYR ALOX5 1384/4885GGPS1 4116/4885PRKDC 2084/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.